Isenman DE - Search Results

1

Structure-function analysis of the C3 binding region of Staphylococcus aureus immune subversion protein Sbi.

Upadhyay A, Burman JD, Clark EA, Leung E, Isenman DE, van den Elsen JM, Bagby S. Upadhyay A, et al. Among authors: isenman de. J Biol Chem. 2008 Aug 8;283(32):22113-20. doi: 10.1074/jbc.M802636200. Epub 2008 Jun 11. J Biol Chem. 2008. PMID: 18550524 Free PMC article.

2

Interaction of human complement with Sbi, a staphylococcal immunoglobulin-binding protein: indications of a novel mechanism of complement evasion by Staphylococcus aureus.

Burman JD, Leung E, Atkins KL, O'Seaghdha MN, Lango L, Bernadó P, Bagby S, Svergun DI, Foster TJ, Isenman DE, van den Elsen JM. Burman JD, et al. Among authors: isenman de. J Biol Chem. 2008 Jun 20;283(25):17579-93. doi: 10.1074/jbc.M800265200. Epub 2008 Apr 22. J Biol Chem. 2008. PMID: 18434316 Free PMC article.

3

Mutational analyses reveal that the staphylococcal immune evasion molecule Sbi and complement receptor 2 (CR2) share overlapping contact residues on C3d: implications for the controversy regarding the CR2/C3d cocrystal structure.

Isenman DE, Leung E, Mackay JD, Bagby S, van den Elsen JM. Isenman DE, et al. J Immunol. 2010 Feb 15;184(4):1946-55. doi: 10.4049/jimmunol.0902919. Epub 2010 Jan 18. J Immunol. 2010. PMID: 20083651

4

A crystal structure of the complex between human complement receptor 2 and its ligand C3d.

van den Elsen JM, Isenman DE. van den Elsen JM, et al. Among authors: isenman de. Science. 2011 Apr 29;332(6029):608-11. doi: 10.1126/science.1201954. Science. 2011. PMID: 21527715

5

X-ray crystal structure of the C4d fragment of human complement component C4.

van den Elsen JM, Martin A, Wong V, Clemenza L, Rose DR, Isenman DE. van den Elsen JM, et al. Among authors: isenman de. J Mol Biol. 2002 Oct 4;322(5):1103-15. doi: 10.1016/s0022-2836(02)00854-9. J Mol Biol. 2002. PMID: 12367531

6

The complement regulator C4b-binding protein (C4BP) interacts with both the C4c and C4dg subfragments of the parent C4b ligand: evidence for synergy in C4BP subsite binding.

Leung E, Blom AM, Clemenza L, Isenman DE. Leung E, et al. Among authors: isenman de. Biochemistry. 2006 Jul 11;45(27):8378-92. doi: 10.1021/bi0603827. Biochemistry. 2006. PMID: 16819837

7

Dual interaction of factor H with C3d and glycosaminoglycans in host-nonhost discrimination by complement.

Kajander T, Lehtinen MJ, Hyvärinen S, Bhattacharjee A, Leung E, Isenman DE, Meri S, Goldman A, Jokiranta TS. Kajander T, et al. Among authors: isenman de. Proc Natl Acad Sci U S A. 2011 Feb 15;108(7):2897-902. doi: 10.1073/pnas.1017087108. Epub 2011 Feb 1. Proc Natl Acad Sci U S A. 2011. PMID: 21285368 Free PMC article.

8

A phage display screen and binding studies with acetylated low density lipoprotein provide evidence for the importance of the scavenger receptor cysteine-rich (SRCR) domain in the ligand-binding function of MARCO.

Chen Y, Sankala M, Ojala JR, Sun Y, Tuuttila A, Isenman DE, Tryggvason K, Pikkarainen T. Chen Y, et al. Among authors: isenman de. J Biol Chem. 2006 May 5;281(18):12767-75. doi: 10.1074/jbc.M513628200. Epub 2006 Mar 7. J Biol Chem. 2006. PMID: 16524885 Free article.

9

Structural requirements for thioester bond formation in human complement component C3. Reassessment of the role of thioester bond integrity on the conformation of C3.

Isaac L, Isenman DE. Isaac L, et al. Among authors: isenman de. J Biol Chem. 1992 May 15;267(14):10062-9. J Biol Chem. 1992. PMID: 1577777 Free article.

10

Mutagenesis of the Arg-Gly-Asp triplet in human complement component C3 does not abolish binding of iC3b to the leukocyte integrin complement receptor type III (CR3, CD11b/CD18).

Taniguchi-Sidle A, Isenman DE. Taniguchi-Sidle A, et al. Among authors: isenman de. J Biol Chem. 1992 Jan 5;267(1):635-43. J Biol Chem. 1992. PMID: 1730624 Free article.

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