Fukaya H - Search Results

1

Discovery of selective and nonpeptidic cathepsin S inhibitors.

Irie O, Ehara T, Iwasaki A, Yokokawa F, Sakaki J, Hirao H, Kanazawa T, Teno N, Horiuchi M, Umemura I, Gunji H, Masuya K, Hitomi Y, Iwasaki G, Nonomura K, Tanabe K, Fukaya H, Kosaka T, Snell CR, Hallett A. Irie O, et al. Among authors: fukaya h. Bioorg Med Chem Lett. 2008 Jul 15;18(14):3959-62. doi: 10.1016/j.bmcl.2008.06.009. Epub 2008 Jun 10. Bioorg Med Chem Lett. 2008. PMID: 18572405

2

Synthesis and structure-activity relationship of novel RXR antagonists: orally active anti-diabetic and anti-obesity agents.

Sakaki J, Kishida M, Konishi K, Gunji H, Toyao A, Matsumoto Y, Kanazawa T, Uchiyama H, Fukaya H, Mitani H, Arai Y, Kimura M. Sakaki J, et al. Among authors: fukaya h. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4804-7. doi: 10.1016/j.bmcl.2007.06.080. Epub 2007 Jun 30. Bioorg Med Chem Lett. 2007. PMID: 17651968

3

Synthesis and structure-activity relationship of RXR antagonists based on the diazepinylbenzoic acid structure.

Sakaki J, Konishi K, Kishida M, Gunji H, Kanazawa T, Uchiyama H, Fukaya H, Mitani H, Kimura M. Sakaki J, et al. Among authors: fukaya h. Bioorg Med Chem Lett. 2007 Sep 1;17(17):4808-11. doi: 10.1016/j.bmcl.2007.06.079. Epub 2007 Jun 30. Bioorg Med Chem Lett. 2007. PMID: 17651969

4

Effect of cathepsin K inhibitors on bone resorption.

Teno N, Masuya K, Ehara T, Kosaka T, Miyake T, Irie O, Hitomi Y, Matsuura N, Umemura I, Iwasaki G, Fukaya H, Toriyama K, Uchiyama N, Nonomura K, Sugiyama I, Kometani M. Teno N, et al. Among authors: fukaya h. J Med Chem. 2008 Sep 11;51(17):5459-62. doi: 10.1021/jm800626a. Epub 2008 Aug 16. J Med Chem. 2008. PMID: 18707091

5

Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain.

Irie O, Kosaka T, Ehara T, Yokokawa F, Kanazawa T, Hirao H, Iwasaki A, Sakaki J, Teno N, Hitomi Y, Iwasaki G, Fukaya H, Nonomura K, Tanabe K, Koizumi S, Uchiyama N, Bevan SJ, Malcangio M, Gentry C, Fox AJ, Yaqoob M, Culshaw AJ, Allan Hallett. Irie O, et al. Among authors: fukaya h. J Med Chem. 2008 Sep 25;51(18):5502-5. doi: 10.1021/jm800839j. J Med Chem. 2008. PMID: 18754655

6

SDZ ENA 713 facilitates central cholinergic function and ameliorates spatial memory impairment in rats.

Ohara T, Tanaka K, Fukaya H, Demura N, Iimura A, Seno N. Ohara T, et al. Among authors: fukaya h. Behav Brain Res. 1997 Feb;83(1-2):229-33. doi: 10.1016/s0166-4328(97)86076-7. Behav Brain Res. 1997. PMID: 9062691

7

A cyclosporin A/maltosyl-alpha-cyclodextrin complex for inhalation therapy of asthma.

Fukaya H, Iimura A, Hoshiko K, Fuyumuro T, Noji S, Nabeshima T. Fukaya H, et al. Eur Respir J. 2003 Aug;22(2):213-9. doi: 10.1183/09031936.03.00018202. Eur Respir J. 2003. PMID: 12952250 Free article.

8

Ameliorating effects of SDZ ENA 713 on age-associated decreases in learning performance and brain choline acetyltransferase activity in rats.

Ohara T, Fukaya H, Itanaka K, Seno N. Ohara T, et al. Among authors: fukaya h. Brain Res Bull. 1997;43(1):39-42. doi: 10.1016/s0361-9230(96)00349-8. Brain Res Bull. 1997. PMID: 9205792

9

Development of tolerance and supersensitivity to phencyclidine in rats after repeated administration of phencyclidine.

Nabeshima T, Fukaya H, Yamaguchi K, Ishikawa K, Furukawa H, Kameyama T. Nabeshima T, et al. Among authors: fukaya h. Eur J Pharmacol. 1987 Mar 3;135(1):23-33. doi: 10.1016/0014-2999(87)90753-9. Eur J Pharmacol. 1987. PMID: 3569423

10

Potentiation of phencyclidine-induced stereotyped behaviors in rats by thiorphan and bestatin.

Hiramatsu M, Nabeshima T, Fukaya H, Furukawa H, Kameyama T. Hiramatsu M, et al. Among authors: fukaya h. Eur J Pharmacol. 1986 Jan 14;120(1):69-74. doi: 10.1016/0014-2999(86)90641-2. Eur J Pharmacol. 1986. PMID: 3456306

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