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Proinflammatory effect of sodium 4-phenylbutyrate in deltaF508-cystic fibrosis transmembrane conductance regulator lung epithelial cells: involvement of extracellular signal-regulated protein kinase 1/2 and c-Jun-NH2-terminal kinase signaling.
Roque T, Boncoeur E, Saint-Criq V, Bonvin E, Clement A, Tabary O, Jacquot J. Roque T, et al. Among authors: boncoeur e. J Pharmacol Exp Ther. 2008 Sep;326(3):949-56. doi: 10.1124/jpet.107.135186. Epub 2008 Jun 23. J Pharmacol Exp Ther. 2008. PMID: 18574003
Mesenchymal stem cells reduce hypoxia-induced apoptosis in alveolar epithelial cells by modulating HIF and ROS hypoxic signaling.
Bernard O, Jeny F, Uzunhan Y, Dondi E, Terfous R, Label R, Sutton A, Larghero J, Vanneaux V, Nunes H, Boncoeur E, Planès C, Dard N. Bernard O, et al. Among authors: boncoeur e. Am J Physiol Lung Cell Mol Physiol. 2018 Mar 1;314(3):L360-L371. doi: 10.1152/ajplung.00153.2017. Epub 2017 Nov 22. Am J Physiol Lung Cell Mol Physiol. 2018. PMID: 29167125 Free article.
HIF-1α triggers ER stress and CHOP-mediated apoptosis in alveolar epithelial cells, a key event in pulmonary fibrosis.
Delbrel E, Soumare A, Naguez A, Label R, Bernard O, Bruhat A, Fafournoux P, Tremblais G, Marchant D, Gille T, Bernaudin JF, Callard P, Kambouchner M, Martinod E, Valeyre D, Uzunhan Y, Planès C, Boncoeur E. Delbrel E, et al. Among authors: boncoeur e. Sci Rep. 2018 Dec 18;8(1):17939. doi: 10.1038/s41598-018-36063-2. Sci Rep. 2018. PMID: 30560874 Free PMC article.
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