Bräuner-Osborne H - Search Results

1

N-Hydroxypyrazolyl glycine derivatives as selective N-methyl-D-aspartic acid receptor ligands.

Clausen RP, Christensen C, Hansen KB, Greenwood JR, Jørgensen L, Micale N, Madsen JC, Nielsen B, Egebjerg J, Bräuner-Osborne H, Traynelis SF, Kristensen JL. Clausen RP, et al. J Med Chem. 2008 Jul 24;51(14):4179-87. doi: 10.1021/jm800025e. Epub 2008 Jun 25. J Med Chem. 2008. PMID: 18578474 Free PMC article.

2

Annulated heterocyclic bioisosteres of norarecoline. Synthesis and molecular pharmacology at five recombinant human muscarinic acetylcholine receptors.

Bräuner-Osborne H, Ebert B, Brann MR, Falch E, Krogsgaard-Larsen P. Bräuner-Osborne H, et al. J Med Chem. 1995 Jun 9;38(12):2188-95. doi: 10.1021/jm00012a019. J Med Chem. 1995. PMID: 7783150

3

A new highly selective metabotropic excitatory amino acid agonist: 2-amino-4-(3-hydroxy-5-methylisoxazol-4-yl)butyric acid.

Bräuner-Osborne H, Sløk FA, Skjaerbaek N, Ebert B, Sekiyama N, Nakanishi S, Krogsgaard-Larsen P. Bräuner-Osborne H, et al. J Med Chem. 1996 Aug 2;39(16):3188-94. doi: 10.1021/jm9602569. J Med Chem. 1996. PMID: 8759641

4

(S)-homo-AMPA, a specific agonist at the mGlu6 subtype of metabotropic glutamic acid receptors.

Ahmadian H, Nielsen B, Bräuner-Osborne H, Johansen TN, Stensbøl TB, Sløk FA, Sekiyama N, Nakanishi S, Krogsgaard-Larsen P, Madsen U. Ahmadian H, et al. J Med Chem. 1997 Oct 24;40(22):3700-5. doi: 10.1021/jm9703597. J Med Chem. 1997. PMID: 9357538

5

Molecular pharmacology of 4-substituted glutamic acid analogues at ionotropic and metabotropic excitatory amino acid receptors.

Bráuner-Osborne H, Nielsen B, Stensbøl TB, Johansen TN, Skjaerbaek N, Krogsgaard-Larsen P. Bráuner-Osborne H, et al. Eur J Pharmacol. 1997 Sep 24;335(2-3):R1-3. doi: 10.1016/s0014-2999(97)01263-6. Eur J Pharmacol. 1997. PMID: 9369383

6

Excitatory amino acid receptor ligands: resolution, absolute stereochemistry, and enantiopharmacology of 2-amino-3-(4-butyl-3-hydroxyisoxazol-5-yl)propionic acid.

Johansen TN, Ebert B, Bräuner-Osborne H, Didriksen M, Christensen IT, Søby KK, Madsen U, Krogsgaard-Larsen P, Brehm L. Johansen TN, et al. J Med Chem. 1998 Mar 12;41(6):930-9. doi: 10.1021/jm9706731. J Med Chem. 1998. PMID: 9526567

7

Molecular pharmacology of homologues of ibotenic acid at cloned metabotropic glutamic acid receptors.

Bräuner-Osborne H, Nielsen B, Krogsgaard-Larsen P. Bräuner-Osborne H, et al. Eur J Pharmacol. 1998 Jun 5;350(2-3):311-6. doi: 10.1016/s0014-2999(98)00246-5. Eur J Pharmacol. 1998. PMID: 9696422

8

Synthesis and pharmacology of N-alkylated derivatives of the excitotoxin ibotenic acid.

Madsen U, Dumpis MA, Bräuner-Osborne H, Piotrovsky LB. Madsen U, et al. Bioorg Med Chem Lett. 1998 Jun 16;8(12):1563-8. doi: 10.1016/s0960-894x(98)00264-9. Bioorg Med Chem Lett. 1998. PMID: 9873391

9

Synthesis and muscarinic receptor pharmacology of a series of 4,5,6,7-tetrahydroisothiazolo[4,5-c]pyridine bioisosteres of arecoline.

Pedersen H, Bräuner-Osborne H, Ball RG, Frydenvang K, Meier E, Bøgesø KP, Krogsgaard-Larsen P. Pedersen H, et al. Bioorg Med Chem. 1999 May;7(5):795-809. doi: 10.1016/s0968-0896(99)00033-4. Bioorg Med Chem. 1999. PMID: 10400332

10

Ionotropic excitatory amino acid receptor ligands. Synthesis and pharmacology of a new amino acid AMPA antagonist.

Madsen U, Sløk FA, Stensbøl TB, Bräuner-Osborne H, Lützhøft HH, Poulsen MV, Eriksen L, Krogsgaard-Larsen P. Madsen U, et al. Eur J Med Chem. 2000 Jan;35(1):69-76. doi: 10.1016/s0223-5234(00)00104-5. Eur J Med Chem. 2000. PMID: 10733604

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