Xie H - Search Results

1

Salvicine triggers DNA double-strand breaks and apoptosis by GSH-depletion-driven H2O2 generation and topoisomerase II inhibition.

Cai YJ, Lu JJ, Zhu H, Xie H, Huang M, Lin LP, Zhang XW, Ding J. Cai YJ, et al. Among authors: xie h. Free Radic Biol Med. 2008 Sep 1;45(5):627-35. doi: 10.1016/j.freeradbiomed.2008.05.017. Epub 2008 May 28. Free Radic Biol Med. 2008. PMID: 18582559

2

Structural modification of an angiogenesis inhibitor discovered from traditional Chinese medicine and a structure-activity relationship study.

Yang SP, Cai YJ, Zhang BL, Tong LJ, Xie H, Wu Y, Lin LP, Ding J, Yue JM. Yang SP, et al. Among authors: xie h. J Med Chem. 2008 Jan 10;51(1):77-85. doi: 10.1021/jm070906g. Epub 2007 Dec 14. J Med Chem. 2008. PMID: 18078313

3

Naturally occurring homoisoflavonoids function as potent protein tyrosine kinase inhibitors by c-Src-based high-throughput screening.

Lin LG, Xie H, Li HL, Tong LJ, Tang CP, Ke CQ, Liu QF, Lin LP, Geng MY, Jiang H, Zhao WM, Ding J, Ye Y. Lin LG, et al. Among authors: xie h. J Med Chem. 2008 Aug 14;51(15):4419-29. doi: 10.1021/jm701501x. Epub 2008 Jul 9. J Med Chem. 2008. PMID: 18610999

4

GA3, a new gambogic acid derivative, exhibits potent antitumor activities in vitro via apoptosis-involved mechanisms.

Xie H, Qin YX, Zhou YL, Tong LJ, Lin LP, Geng MY, Duan WH, Ding J. Xie H, et al. Acta Pharmacol Sin. 2009 Mar;30(3):346-54. doi: 10.1038/aps.2009.3. Acta Pharmacol Sin. 2009. PMID: 19262558 Free PMC article.

5

Carboline alkaloids from Trigonostemon lii.

Hu XJ, Di YT, Wang YH, Kong LY, Gao S, Li CS, Liu HY, He HP, Ding J, Xie H, Hao XJ. Hu XJ, et al. Among authors: xie h. Planta Med. 2009 Aug;75(10):1157-61. doi: 10.1055/s-0029-1185505. Epub 2009 Mar 26. Planta Med. 2009. PMID: 19326327

6

BB, a new EGFR inhibitor, exhibits prominent anti-angiogenesis and antitumor activities.

Sun QM, Miao ZH, Lin LP, Gui M, Zhu CH, Xie H, Duan WH, Ding J. Sun QM, et al. Among authors: xie h. Cancer Biol Ther. 2009 Sep;8(17):1640-7. doi: 10.4161/cbt.8.17.9205. Epub 2009 Sep 6. Cancer Biol Ther. 2009. PMID: 19625781 Free article.

7

A new class of naphthalimide-based antitumor agents that inhibit topoisomerase II and induce lysosomal membrane permeabilization and apoptosis.

Chen Z, Liang X, Zhang H, Xie H, Liu J, Xu Y, Zhu W, Wang Y, Wang X, Tan S, Kuang D, Qian X. Chen Z, et al. Among authors: xie h. J Med Chem. 2010 Mar 25;53(6):2589-600. doi: 10.1021/jm100025u. J Med Chem. 2010. PMID: 20170164

8

Discovery and SAR of thiazolidine-2,4-dione analogues as insulin-like growth factor-1 receptor (IGF-1R) inhibitors via hierarchical virtual screening.

Liu X, Xie H, Luo C, Tong L, Wang Y, Peng T, Ding J, Jiang H, Li H. Liu X, et al. Among authors: xie h. J Med Chem. 2010 Mar 25;53(6):2661-5. doi: 10.1021/jm901798e. J Med Chem. 2010. PMID: 20178321 Free article.

9

Acenaphtho[1,2-b]pyrrole-based selective fibroblast growth factor receptors 1 (FGFR1) inhibitors: design, synthesis, and biological activity.

Chen Z, Wang X, Zhu W, Cao X, Tong L, Li H, Xie H, Xu Y, Tan S, Kuang D, Ding J, Qian X. Chen Z, et al. Among authors: xie h. J Med Chem. 2011 Jun 9;54(11):3732-45. doi: 10.1021/jm200258t. Epub 2011 May 13. J Med Chem. 2011. PMID: 21517068

10

Establishment of platform for screening insulin-like growth factor-1 receptor inhibitors and evaluation of novel inhibitors.

Tong LJ, Xie H, Peng T, Liu XF, Xin XL, Huang X, Chen SM, Liu HY, Li HL, Geng MY, Yin M, Ding J. Tong LJ, et al. Among authors: xie h. Acta Pharmacol Sin. 2011 Jul;32(7):930-8. doi: 10.1038/aps.2011.23. Epub 2011 Jun 6. Acta Pharmacol Sin. 2011. PMID: 21643004 Free PMC article.

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