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Page 1
Dynamic functional relay between insulin receptor substrate 1 and 2 in hepatic insulin signaling during fasting and feeding.
Kubota N, Kubota T, Itoh S, Kumagai H, Kozono H, Takamoto I, Mineyama T, Ogata H, Tokuyama K, Ohsugi M, Sasako T, Moroi M, Sugi K, Kakuta S, Iwakura Y, Noda T, Ohnishi S, Nagai R, Tobe K, Terauchi Y, Ueki K, Kadowaki T. Kubota N, et al. Among authors: noda t. Cell Metab. 2008 Jul;8(1):49-64. doi: 10.1016/j.cmet.2008.05.007. Cell Metab. 2008. PMID: 18590692 Free article.
Insulin receptor substrate 2 plays a crucial role in beta cells and the hypothalamus.
Kubota N, Terauchi Y, Tobe K, Yano W, Suzuki R, Ueki K, Takamoto I, Satoh H, Maki T, Kubota T, Moroi M, Okada-Iwabu M, Ezaki O, Nagai R, Ueta Y, Kadowaki T, Noda T. Kubota N, et al. Among authors: noda t. J Clin Invest. 2004 Oct;114(7):917-27. doi: 10.1172/JCI21484. J Clin Invest. 2004. PMID: 15467830 Free PMC article.
Adiponectin stimulates AMP-activated protein kinase in the hypothalamus and increases food intake.
Kubota N, Yano W, Kubota T, Yamauchi T, Itoh S, Kumagai H, Kozono H, Takamoto I, Okamoto S, Shiuchi T, Suzuki R, Satoh H, Tsuchida A, Moroi M, Sugi K, Noda T, Ebinuma H, Ueta Y, Kondo T, Araki E, Ezaki O, Nagai R, Tobe K, Terauchi Y, Ueki K, Minokoshi Y, Kadowaki T. Kubota N, et al. Among authors: noda t. Cell Metab. 2007 Jul;6(1):55-68. doi: 10.1016/j.cmet.2007.06.003. Cell Metab. 2007. PMID: 17618856 Free article.
Molecular mechanism of moderate insulin resistance in adiponectin-knockout mice.
Yano W, Kubota N, Itoh S, Kubota T, Awazawa M, Moroi M, Sugi K, Takamoto I, Ogata H, Tokuyama K, Noda T, Terauchi Y, Ueki K, Kadowaki T. Yano W, et al. Among authors: noda t. Endocr J. 2008 Jul;55(3):515-22. doi: 10.1507/endocrj.k08e-093. Epub 2008 Apr 30. Endocr J. 2008. PMID: 18446001 Free article.
Rimonabant ameliorates insulin resistance via both adiponectin-dependent and adiponectin-independent pathways.
Watanabe T, Kubota N, Ohsugi M, Kubota T, Takamoto I, Iwabu M, Awazawa M, Katsuyama H, Hasegawa C, Tokuyama K, Moroi M, Sugi K, Yamauchi T, Noda T, Nagai R, Terauchi Y, Tobe K, Ueki K, Kadowaki T. Watanabe T, et al. Among authors: noda t. J Biol Chem. 2009 Jan 16;284(3):1803-12. doi: 10.1074/jbc.M807120200. Epub 2008 Nov 13. J Biol Chem. 2009. PMID: 19008231 Free article.
Differential hepatic distribution of insulin receptor substrates causes selective insulin resistance in diabetes and obesity.
Kubota N, Kubota T, Kajiwara E, Iwamura T, Kumagai H, Watanabe T, Inoue M, Takamoto I, Sasako T, Kumagai K, Kohjima M, Nakamuta M, Moroi M, Sugi K, Noda T, Terauchi Y, Ueki K, Kadowaki T. Kubota N, et al. Among authors: noda t. Nat Commun. 2016 Oct 6;7:12977. doi: 10.1038/ncomms12977. Nat Commun. 2016. PMID: 27708333 Free PMC article.
Disruption of adiponectin causes insulin resistance and neointimal formation.
Kubota N, Terauchi Y, Yamauchi T, Kubota T, Moroi M, Matsui J, Eto K, Yamashita T, Kamon J, Satoh H, Yano W, Froguel P, Nagai R, Kimura S, Kadowaki T, Noda T. Kubota N, et al. Among authors: noda t. J Biol Chem. 2002 Jul 19;277(29):25863-6. doi: 10.1074/jbc.C200251200. Epub 2002 May 24. J Biol Chem. 2002. PMID: 12032136 Free article.
Pioglitazone ameliorates insulin resistance and diabetes by both adiponectin-dependent and -independent pathways.
Kubota N, Terauchi Y, Kubota T, Kumagai H, Itoh S, Satoh H, Yano W, Ogata H, Tokuyama K, Takamoto I, Mineyama T, Ishikawa M, Moroi M, Sugi K, Yamauchi T, Ueki K, Tobe K, Noda T, Nagai R, Kadowaki T. Kubota N, et al. Among authors: noda t. J Biol Chem. 2006 Mar 31;281(13):8748-55. doi: 10.1074/jbc.M505649200. Epub 2006 Jan 23. J Biol Chem. 2006. PMID: 16431926 Free article.
Insulin- and Lipopolysaccharide-Mediated Signaling in Adipose Tissue Macrophages Regulates Postprandial Glycemia through Akt-mTOR Activation.
Toda G, Soeda K, Okazaki Y, Kobayashi N, Masuda Y, Arakawa N, Suwanai H, Masamoto Y, Izumida Y, Kamei N, Sasako T, Suzuki R, Kubota T, Kubota N, Kurokawa M, Tobe K, Noda T, Honda K, Accili D, Yamauchi T, Kadowaki T, Ueki K. Toda G, et al. Among authors: noda t. Mol Cell. 2020 Jul 2;79(1):43-53.e4. doi: 10.1016/j.molcel.2020.04.033. Epub 2020 May 27. Mol Cell. 2020. PMID: 32464093 Free article.
Role of hepatic STAT3 in brain-insulin action on hepatic glucose production.
Inoue H, Ogawa W, Asakawa A, Okamoto Y, Nishizawa A, Matsumoto M, Teshigawara K, Matsuki Y, Watanabe E, Hiramatsu R, Notohara K, Katayose K, Okamura H, Kahn CR, Noda T, Takeda K, Akira S, Inui A, Kasuga M. Inoue H, et al. Among authors: noda t. Cell Metab. 2006 Apr;3(4):267-75. doi: 10.1016/j.cmet.2006.02.009. Cell Metab. 2006. PMID: 16581004 Free article.
2,431 results