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Hydroxamic acid analogue histone deacetylase inhibitors attenuate estrogen receptor-alpha levels and transcriptional activity: a result of hyperacetylation and inhibition of chaperone function of heat shock protein 90.
Fiskus W, Ren Y, Mohapatra A, Bali P, Mandawat A, Rao R, Herger B, Yang Y, Atadja P, Wu J, Bhalla K. Fiskus W, et al. Among authors: yang y. Clin Cancer Res. 2007 Aug 15;13(16):4882-90. doi: 10.1158/1078-0432.CCR-06-3093. Clin Cancer Res. 2007. PMID: 17699868
Panobinostat treatment depletes EZH2 and DNMT1 levels and enhances decitabine mediated de-repression of JunB and loss of survival of human acute leukemia cells.
Fiskus W, Buckley K, Rao R, Mandawat A, Yang Y, Joshi R, Wang Y, Balusu R, Chen J, Koul S, Joshi A, Upadhyay S, Atadja P, Bhalla KN. Fiskus W, et al. Among authors: yang y. Cancer Biol Ther. 2009 May;8(10):939-50. doi: 10.4161/cbt.8.10.8213. Epub 2009 May 18. Cancer Biol Ther. 2009. PMID: 19279403 Free PMC article.
Co-treatment with heat shock protein 90 inhibitor 17-dimethylaminoethylamino-17-demethoxygeldanamycin (DMAG) and vorinostat: a highly active combination against human mantle cell lymphoma (MCL) cells.
Rao R, Lee P, Fiskus W, Yang Y, Joshi R, Wang Y, Buckley K, Balusu R, Chen J, Koul S, Joshi A, Upadhyay S, Tao J, Sotomayor E, Bhalla KN. Rao R, et al. Among authors: yang y. Cancer Biol Ther. 2009 Jul;8(13):1273-80. doi: 10.4161/cbt.8.13.8726. Cancer Biol Ther. 2009. PMID: 19440035 Free PMC article.
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