Chen L - Search Results

1

Design, synthesis, and antihepatocellular carcinoma activity of nitric oxide releasing derivatives of oleanolic acid.

Chen L, Zhang Y, Kong X, Lan E, Huang Z, Peng S, Kaufman DL, Tian J. Chen L, et al. J Med Chem. 2008 Aug 14;51(15):4834-8. doi: 10.1021/jm800167u. Epub 2008 Jul 4. J Med Chem. 2008. PMID: 18598019 Free PMC article.

2

Synthesis and biological evaluation of nitric oxide-releasing derivatives of oleanolic acid as inhibitors of HepG2 cell apoptosis.

Chen L, Zhang Y, Kong X, Peng S, Tian J. Chen L, et al. Bioorg Med Chem Lett. 2007 Jun 1;17(11):2979-82. doi: 10.1016/j.bmcl.2007.03.068. Epub 2007 Mar 25. Bioorg Med Chem Lett. 2007. PMID: 17446070 Free PMC article.

3

Synthesis and anti-human hepatocellular carcinoma activity of new nitric oxide-releasing glycosyl derivatives of oleanolic acid.

Huang Z, Zhang Y, Zhao L, Jing Y, Lai Y, Zhang L, Guo Q, Yuan S, Zhang J, Chen L, Peng S, Tian J. Huang Z, et al. Among authors: chen l. Org Biomol Chem. 2010 Feb 7;8(3):632-9. doi: 10.1039/b918846k. Epub 2009 Dec 8. Org Biomol Chem. 2010. PMID: 20090981

4

[Synthesis and biological evaluation of nitrate-oleanolic acid hybrids as inhibitors of HepG2 cell apoptosis].

Chen L, Shang J, Wang ZF, Zhang YH, Tian JD. Chen L, et al. Yao Xue Xue Bao. 2010 Dec;45(12):1516-22. Yao Xue Xue Bao. 2010. PMID: 21351491 Chinese.

5

Synthesis and biological evaluation of farnesylthiosalicylamides as potential anti-tumor agents.

Ling Y, Wang Z, Zhu H, Wang X, Zhang W, Wang X, Chen L, Huang Z, Zhang Y. Ling Y, et al. Among authors: chen l. Bioorg Med Chem. 2014 Jan 1;22(1):374-80. doi: 10.1016/j.bmc.2013.11.013. Epub 2013 Nov 15. Bioorg Med Chem. 2014. PMID: 24300920

6

Synthesis and biological evaluation of hybrids from farnesylthiosalicylic acid and hydroxylcinnamic acid with dual inhibitory activities of Ras-related signaling and phosphorylated NF-κB.

Ling Y, Wang Z, Wang X, Zhao Y, Zhang W, Wang X, Chen L, Huang Z, Zhang Y. Ling Y, et al. Among authors: chen l. Org Biomol Chem. 2014 Jul 7;12(25):4517-30. doi: 10.1039/c4ob00023d. Org Biomol Chem. 2014. PMID: 24848877

7

(S)-ZJM-289, a nitric oxide-releasing derivative of 3-n-butylphthalide, protects against ischemic neuronal injury by attenuating mitochondrial dysfunction and associated cell death.

Zhao Q, Zhang C, Wang X, Chen L, Ji H, Zhang Y. Zhao Q, et al. Among authors: chen l. Neurochem Int. 2012 Jan;60(2):134-44. doi: 10.1016/j.neuint.2011.11.013. Epub 2011 Nov 28. Neurochem Int. 2012. PMID: 22142531

8

O²-(2,4-dinitrophenyl)diazeniumdiolates derivatives: Design, synthesis, cytotoxic evaluation and reversing MDR in MCF-7/ADR cells.

Li Q, Zou P, Sun J, Chen L. Li Q, et al. Among authors: chen l. Eur J Med Chem. 2018 Jan 1;143:732-744. doi: 10.1016/j.ejmech.2017.11.081. Eur J Med Chem. 2018. PMID: 29220794

9

Novel anticancer hybrids from diazen-1-ium-1,2-diolate nitric oxide donor and ROS inducer plumbagin: Design, synthesis and biological evaluations.

Bao N, Ou J, Li N, Zou P, Sun J, Chen L. Bao N, et al. Among authors: chen l. Eur J Med Chem. 2018 Jun 25;154:1-8. doi: 10.1016/j.ejmech.2018.04.047. Epub 2018 Apr 25. Eur J Med Chem. 2018. PMID: 29772386

10

Discovery of novel NO-releasing celastrol derivatives with Hsp90 inhibition and cytotoxic activities.

Li N, Xu M, Bao N, Shi W, Li Q, Zhang X, Sun J, Chen L. Li N, et al. Among authors: chen l. Eur J Med Chem. 2018 Dec 5;160:1-8. doi: 10.1016/j.ejmech.2018.10.013. Epub 2018 Oct 6. Eur J Med Chem. 2018. PMID: 30316059

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