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An analysis of the results from Two-Generation Reproduction Toxicity Studies to assess the value of mating animals of the second (F1) generation for the detection of adverse treatment-related effects on reproductive performance.
Myers DP, Willoughby CR, Bottomley AM, Buschmann J. Myers DP, et al. Among authors: willoughby cr. Reprod Toxicol. 2008 Sep;26(1):47-50. doi: 10.1016/j.reprotox.2008.06.004. Epub 2008 Jun 18. Reprod Toxicol. 2008. PMID: 18602985
Safety evaluation of Streptomyces murinus glucose isomerase.
Ashby R, Hjortkjaer RK, Stavnsbjerg M, Gurtler H, Pedersen PB, Bootman J, Hodson-Walker G, Tesh JM, Willoughby CR, West H, et al. Ashby R, et al. Among authors: willoughby cr. Toxicol Lett. 1987 Mar;36(1):23-35. doi: 10.1016/0378-4274(87)90037-3. Toxicol Lett. 1987. PMID: 3564067
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