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Phase 1 trial of malaria transmission blocking vaccine candidates Pfs25 and Pvs25 formulated with montanide ISA 51.
Wu Y, Ellis RD, Shaffer D, Fontes E, Malkin EM, Mahanty S, Fay MP, Narum D, Rausch K, Miles AP, Aebig J, Orcutt A, Muratova O, Song G, Lambert L, Zhu D, Miura K, Long C, Saul A, Miller LH, Durbin AP. Wu Y, et al. Among authors: lambert l. PLoS One. 2008 Jul 9;3(7):e2636. doi: 10.1371/journal.pone.0002636. PLoS One. 2008. PMID: 18612426 Free PMC article. Clinical Trial.
Pfs230 yields higher malaria transmission-blocking vaccine activity than Pfs25 in humans but not mice.
Healy SA, Anderson C, Swihart BJ, Mwakingwe A, Gabriel EE, Decederfelt H, Hobbs CV, Rausch KM, Zhu D, Muratova O, Herrera R, Scaria PV, MacDonald NJ, Lambert LE, Zaidi I, Coelho CH, Renn JP, Wu Y, Narum DL, Duffy PE. Healy SA, et al. Among authors: lambert le. J Clin Invest. 2021 Apr 1;131(7):e146221. doi: 10.1172/JCI146221. J Clin Invest. 2021. PMID: 33561016 Free PMC article. Clinical Trial.
Immunogenicity of self-associated aggregates and chemically cross-linked conjugates of the 42 kDa Plasmodium falciparum merozoite surface protein-1.
Qian F, Reiter K, Zhang Y, Shimp RL Jr, Nguyen V, Aebig JA, Rausch KM, Zhu D, Lambert L, Mullen GE, Martin LB, Long CA, Miller LH, Narum DL. Qian F, et al. Among authors: lambert l. PLoS One. 2012;7(6):e36996. doi: 10.1371/journal.pone.0036996. Epub 2012 Jun 4. PLoS One. 2012. PMID: 22675476 Free PMC article.
A class of tricyclic compounds blocking malaria parasite oocyst development and transmission.
Eastman RT, Pattaradilokrat S, Raj DK, Dixit S, Deng B, Miura K, Yuan J, Tanaka TQ, Johnson RL, Jiang H, Huang R, Williamson KC, Lambert LE, Long C, Austin CP, Wu Y, Su XZ. Eastman RT, et al. Among authors: lambert le. Antimicrob Agents Chemother. 2013 Jan;57(1):425-35. doi: 10.1128/AAC.00920-12. Epub 2012 Nov 5. Antimicrob Agents Chemother. 2013. PMID: 23129054 Free PMC article.
A recombinant vaccine expressed in the milk of transgenic mice protects Aotus monkeys from a lethal challenge with Plasmodium falciparum.
Stowers AW, Chen Lh LH, Zhang Y, Kennedy MC, Zou L, Lambert L, Rice TJ, Kaslow DC, Saul A, Long CA, Meade H, Miller LH. Stowers AW, et al. Among authors: lambert l. Proc Natl Acad Sci U S A. 2002 Jan 8;99(1):339-44. doi: 10.1073/pnas.012590199. Epub 2001 Dec 18. Proc Natl Acad Sci U S A. 2002. PMID: 11752405 Free PMC article.
1,106 results