Yu S - Search Results

1

Binding of recombinant but not endogenous prion protein to DNA causes DNA internalization and expression in mammalian cells.

Yin S, Fan X, Yu S, Li C, Sy MS. Yin S, et al. Among authors: yu s. J Biol Chem. 2008 Sep 12;283(37):25446-25454. doi: 10.1074/jbc.M800814200. Epub 2008 Jul 11. J Biol Chem. 2008. PMID: 18622017 Free PMC article.

2

Prion proteins with insertion mutations have altered N-terminal conformation and increased ligand binding activity and are more susceptible to oxidative attack.

Yin S, Yu S, Li C, Wong P, Chang B, Xiao F, Kang SC, Yan H, Xiao G, Grassi J, Tien P, Sy MS. Yin S, et al. Among authors: yu s. J Biol Chem. 2006 Apr 21;281(16):10698-705. doi: 10.1074/jbc.M511819200. Epub 2006 Feb 14. J Biol Chem. 2006. PMID: 16478730 Free article.

3

Aggregation of prion protein with insertion mutations is proportional to the number of inserts.

Yu S, Yin S, Li C, Wong P, Chang B, Xiao F, Kang SC, Yan H, Xiao G, Tien P, Sy MS. Yu S, et al. Biochem J. 2007 Apr 15;403(2):343-51. doi: 10.1042/BJ20061592. Biochem J. 2007. PMID: 17187581 Free PMC article.

4

Human prion proteins with pathogenic mutations share common conformational changes resulting in enhanced binding to glycosaminoglycans.

Yin S, Pham N, Yu S, Li C, Wong P, Chang B, Kang SC, Biasini E, Tien P, Harris DA, Sy MS. Yin S, et al. Among authors: yu s. Proc Natl Acad Sci U S A. 2007 May 1;104(18):7546-51. doi: 10.1073/pnas.0610827104. Epub 2007 Apr 24. Proc Natl Acad Sci U S A. 2007. PMID: 17456603 Free PMC article.

5

Normal cellular prion protein with a methionine at position 129 has a more exposed helix 1 and is more prone to aggregate.

Pham N, Yin S, Yu S, Wong P, Kang SC, Li C, Sy MS. Pham N, et al. Among authors: yu s. Biochem Biophys Res Commun. 2008 Apr 18;368(4):875-81. doi: 10.1016/j.bbrc.2008.01.172. Epub 2008 Feb 12. Biochem Biophys Res Commun. 2008. PMID: 18275852

6

Ligand binding promotes prion protein aggregation--role of the octapeptide repeats.

Yu S, Yin S, Pham N, Wong P, Kang SC, Petersen RB, Li C, Sy MS. Yu S, et al. FEBS J. 2008 Nov;275(22):5564-75. doi: 10.1111/j.1742-4658.2008.06680.x. FEBS J. 2008. PMID: 18959744 Free PMC article.

7

Binding of pro-prion to filamin A disrupts cytoskeleton and correlates with poor prognosis in pancreatic cancer.

Li C, Yu S, Nakamura F, Yin S, Xu J, Petrolla AA, Singh N, Tartakoff A, Abbott DW, Xin W, Sy MS. Li C, et al. Among authors: yu s. J Clin Invest. 2009 Sep;119(9):2725-36. doi: 10.1172/JCI39542. Epub 2009 Aug 17. J Clin Invest. 2009. PMID: 19690385 Free PMC article.

8

Pro-prion binds filamin A, facilitating its interaction with integrin beta1, and contributes to melanomagenesis.

Li C, Yu S, Nakamura F, Pentikäinen OT, Singh N, Yin S, Xin W, Sy MS. Li C, et al. Among authors: yu s. J Biol Chem. 2010 Sep 24;285(39):30328-39. doi: 10.1074/jbc.M110.147413. Epub 2010 Jul 21. J Biol Chem. 2010. PMID: 20650901 Free PMC article.

9

The fatal attraction between pro-prion and filamin A: prion as a marker in human cancers.

Sy MS, Li C, Yu S, Xin W. Sy MS, et al. Among authors: yu s. Biomark Med. 2010 Jun;4(3):453-64. doi: 10.2217/bmm.10.14. Biomark Med. 2010. PMID: 20550479 Free PMC article.

10

Cellular Prion Protein Mediates Pancreatic Cancer Cell Survival and Invasion through Association with and Enhanced Signaling of Notch1.

Wang Y, Yu S, Huang D, Cui M, Hu H, Zhang L, Wang W, Parameswaran N, Jackson M, Osborne B, Bedogni B, Li C, Sy MS, Xin W, Zhou L. Wang Y, et al. Among authors: yu s. Am J Pathol. 2016 Nov;186(11):2945-2956. doi: 10.1016/j.ajpath.2016.07.010. Epub 2016 Sep 14. Am J Pathol. 2016. PMID: 27639164 Free PMC article.

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