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Page 1
Discovery of diacylphloroglucinols as a new class of GPR40 (FFAR1) agonists.
Bharate SB, Rodge A, Joshi RK, Kaur J, Srinivasan S, Kumar SS, Kulkarni-Almeida A, Balachandran S, Balakrishnan A, Vishwakarma RA. Bharate SB, et al. Bioorg Med Chem Lett. 2008 Dec 15;18(24):6357-61. doi: 10.1016/j.bmcl.2008.10.085. Epub 2008 Nov 1. Bioorg Med Chem Lett. 2008. PMID: 18993064
Novel leads from Heliotropium ovalifolium, 4,7,8-trimethoxy-naphthalene-2-carboxylic acid and 6-hydroxy-5,7-dimethoxy-naphthalene-2-carbaldehyde show specific IL-6 inhibitory activity in THP-1 cells and primary human monocytes.
Kulkarni-Almeida A, Suthar A, Goswami H, Vishwakarma R, Chauhan VS, Balakrishnan A, Sharma S. Kulkarni-Almeida A, et al. Phytomedicine. 2008 Dec;15(12):1079-86. doi: 10.1016/j.phymed.2008.04.013. Epub 2008 Jun 25. Phytomedicine. 2008. PMID: 18583119
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Khanna S, Burudkar S, Bajaj K, Shah P, Keche A, Ghosh U, Desai A, Srivastava A, Kulkarni-Almeida A, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Nemmani KV, Tannu P, Damre A, B-Rao C, Sharma R, Sivaramakrishnan H. Khanna S, et al. Among authors: kulkarni almeida a. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7543-6. doi: 10.1016/j.bmcl.2012.10.029. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23122864
Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133 produced by Streptomyces strain PM0324667.
Kulkarni-Almeida AA, Brahma MK, Padmanabhan P, Mishra PD, Parab RR, Gaikwad NV, Thakkar CS, Tokdar P, Ranadive PV, Nair AS, Damre AA, Bahirat UA, Deshmukh NJ, Doshi LS, Dixit AV, George SD, Vishwakarma RA, Nemmani KV, Mahajan GB. Kulkarni-Almeida AA, et al. AMB Express. 2011 Nov 21;1(1):42. doi: 10.1186/2191-0855-1-42. AMB Express. 2011. PMID: 22104600 Free PMC article.
Lead optimization of isocytosine-derived xanthine oxidase inhibitors.
Bajaj K, Burudkar S, Shah P, Keche A, Ghosh U, Tannu P, Khanna S, Srivastava A, Deshmukh NJ, Dixit A, Ahire Y, Damre A, Nemmani KV, Kulkarni-Almeida A, B-Rao C, Sharma R, Sivaramakrishnan H. Bajaj K, et al. Among authors: kulkarni almeida a. Bioorg Med Chem Lett. 2013 Feb 1;23(3):834-8. doi: 10.1016/j.bmcl.2012.11.057. Epub 2012 Nov 29. Bioorg Med Chem Lett. 2013. PMID: 23265878
Discovery of tetrahydrocarbazoles as dual pERK and pRb inhibitors.
Kulkarni MR, Mane MS, Ghosh U, Sharma R, Lad NP, Srivastava A, Kulkarni-Almeida A, Kharkar PS, Khedkar VM, Pandit SS. Kulkarni MR, et al. Among authors: kulkarni almeida a. Eur J Med Chem. 2017 Jul 7;134:366-378. doi: 10.1016/j.ejmech.2017.02.062. Epub 2017 Mar 2. Eur J Med Chem. 2017. PMID: 28431342
18 results