Koch WJ - Search Results

1

G protein-coupled receptor kinase 2 ablation in cardiac myocytes before or after myocardial infarction prevents heart failure.

Raake PW, Vinge LE, Gao E, Boucher M, Rengo G, Chen X, DeGeorge BR Jr, Matkovich S, Houser SR, Most P, Eckhart AD, Dorn GW 2nd, Koch WJ. Raake PW, et al. Among authors: koch wj. Circ Res. 2008 Aug 15;103(4):413-22. doi: 10.1161/CIRCRESAHA.107.168336. Epub 2008 Jul 17. Circ Res. 2008. PMID: 18635825 Free PMC article.

2

Reciprocal in vivo regulation of myocardial G protein-coupled receptor kinase expression by beta-adrenergic receptor stimulation and blockade.

Iaccarino G, Tomhave ED, Lefkowitz RJ, Koch WJ. Iaccarino G, et al. Among authors: koch wj. Circulation. 1998 Oct 27;98(17):1783-9. doi: 10.1161/01.cir.98.17.1783. Circulation. 1998. PMID: 9788834

3

Coupling of beta2-adrenoceptor to Gi proteins and its physiological relevance in murine cardiac myocytes.

Xiao RP, Avdonin P, Zhou YY, Cheng H, Akhter SA, Eschenhagen T, Lefkowitz RJ, Koch WJ, Lakatta EG. Xiao RP, et al. Among authors: koch wj. Circ Res. 1999 Jan 8-22;84(1):43-52. doi: 10.1161/01.res.84.1.43. Circ Res. 1999. PMID: 9915773

4

The myocardial beta-adrenergic system in spontaneously hypertensive heart failure (SHHF) rats.

Anderson KM, Eckhart AD, Willette RN, Koch WJ. Anderson KM, et al. Among authors: koch wj. Hypertension. 1999 Jan;33(1 Pt 2):402-7. doi: 10.1161/01.hyp.33.1.402. Hypertension. 1999. PMID: 9931137

5

Low- and high-level transgenic expression of beta2-adrenergic receptors differentially affect cardiac hypertrophy and function in Galphaq-overexpressing mice.

Dorn GW 2nd, Tepe NM, Lorenz JN, Koch WJ, Liggett SB. Dorn GW 2nd, et al. Among authors: koch wj. Proc Natl Acad Sci U S A. 1999 May 25;96(11):6400-5. doi: 10.1073/pnas.96.11.6400. Proc Natl Acad Sci U S A. 1999. PMID: 10339599 Free PMC article.

6

In vivo inhibition of elevated myocardial beta-adrenergic receptor kinase activity in hybrid transgenic mice restores normal beta-adrenergic signaling and function.

Akhter SA, Eckhart AD, Rockman HA, Shotwell K, Lefkowitz RJ, Koch WJ. Akhter SA, et al. Among authors: koch wj. Circulation. 1999 Aug 10;100(6):648-53. doi: 10.1161/01.cir.100.6.648. Circulation. 1999. PMID: 10441103

7

Overexpression of the cardiac beta(2)-adrenergic receptor and expression of a beta-adrenergic receptor kinase-1 (betaARK1) inhibitor both increase myocardial contractility but have differential effects on susceptibility to ischemic injury.

Cross HR, Steenbergen C, Lefkowitz RJ, Koch WJ, Murphy E. Cross HR, et al. Among authors: koch wj. Circ Res. 1999 Nov 26;85(11):1077-84. doi: 10.1161/01.res.85.11.1077. Circ Res. 1999. PMID: 10571539

8

Hybrid transgenic mice reveal in vivo specificity of G protein-coupled receptor kinases in the heart.

Eckhart AD, Duncan SJ, Penn RB, Benovic JL, Lefkowitz RJ, Koch WJ. Eckhart AD, et al. Among authors: koch wj. Circ Res. 2000 Jan 7-21;86(1):43-50. doi: 10.1161/01.res.86.1.43. Circ Res. 2000. PMID: 10625304

9

Vascular beta-adrenergic receptor adenylyl cyclase system in maturation and aging.

Gaballa MA, Eckhart AD, Koch WJ, Goldman S. Gaballa MA, et al. Among authors: koch wj. J Mol Cell Cardiol. 2000 Sep;32(9):1745-55. doi: 10.1006/jmcc.2000.1210. J Mol Cell Cardiol. 2000. PMID: 10966835

10

Physiological induction of a beta-adrenergic receptor kinase inhibitor transgene preserves ss-adrenergic responsiveness in pressure-overload cardiac hypertrophy.

Manning BS, Shotwell K, Mao L, Rockman HA, Koch WJ. Manning BS, et al. Among authors: koch wj. Circulation. 2000 Nov 28;102(22):2751-7. doi: 10.1161/01.cir.102.22.2751. Circulation. 2000. PMID: 11094043

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