Abdel-Hafiz H - Search Results

1

Progesterone receptor action: translating studies in breast cancer models to clinical insights.

Lange CA, Sartorius CA, Abdel-Hafiz H, Spillman MA, Horwitz KB, Jacobsen BM. Lange CA, et al. Adv Exp Med Biol. 2008;630:94-111. Adv Exp Med Biol. 2008. PMID: 18637487 Review.

2

Control of progesterone receptor transcriptional synergy by SUMOylation and deSUMOylation.

Abdel-Hafiz HA, Horwitz KB. Abdel-Hafiz HA, et al. BMC Mol Biol. 2012 Mar 22;13:10. doi: 10.1186/1471-2199-13-10. BMC Mol Biol. 2012. PMID: 22439847 Free PMC article.

3

Post-translational modifications of the progesterone receptors.

Abdel-Hafiz HA, Horwitz KB. Abdel-Hafiz HA, et al. J Steroid Biochem Mol Biol. 2014 Mar;140:80-9. doi: 10.1016/j.jsbmb.2013.12.008. Epub 2013 Dec 12. J Steroid Biochem Mol Biol. 2014. PMID: 24333793 Free PMC article. Review.

4

Regulation of the SUMO pathway sensitizes differentiating human endometrial stromal cells to progesterone.

Jones MC, Fusi L, Higham JH, Abdel-Hafiz H, Horwitz KB, Lam EW, Brosens JJ. Jones MC, et al. Proc Natl Acad Sci U S A. 2006 Oct 31;103(44):16272-7. doi: 10.1073/pnas.0603002103. Epub 2006 Oct 19. Proc Natl Acad Sci U S A. 2006. PMID: 17053081 Free PMC article.

5

Role of epigenetic modifications in luminal breast cancer.

Abdel-Hafiz HA, Horwitz KB. Abdel-Hafiz HA, et al. Epigenomics. 2015 Aug;7(5):847-62. doi: 10.2217/epi.15.10. Epub 2015 Feb 17. Epigenomics. 2015. PMID: 25689414 Free PMC article. Review.

6

Progesterone receptors (PR)-B and -A regulate transcription by different mechanisms: AF-3 exerts regulatory control over coactivator binding to PR-B.

Tung L, Abdel-Hafiz H, Shen T, Harvell DM, Nitao LK, Richer JK, Sartorius CA, Takimoto GS, Horwitz KB. Tung L, et al. Mol Endocrinol. 2006 Nov;20(11):2656-70. doi: 10.1210/me.2006-0105. Epub 2006 Jun 8. Mol Endocrinol. 2006. PMID: 16762974

7

Mechanisms underlying the control of progesterone receptor transcriptional activity by SUMOylation.

Abdel-Hafiz H, Dudevoir ML, Horwitz KB. Abdel-Hafiz H, et al. J Biol Chem. 2009 Apr 3;284(14):9099-108. doi: 10.1074/jbc.M805226200. Epub 2009 Feb 11. J Biol Chem. 2009. PMID: 19211567 Free PMC article.

8

Modeling luminal breast cancer heterogeneity: combination therapy to suppress a hormone receptor-negative, cytokeratin 5-positive subpopulation in luminal disease.

Knox AJ, Scaling AL, Pinto MP, Bliesner BS, Haughian JM, Abdel-Hafiz HA, Horwitz KB. Knox AJ, et al. Breast Cancer Res. 2014 Aug 13;16(4):418. doi: 10.1186/s13058-014-0418-6. Breast Cancer Res. 2014. PMID: 25116921 Free PMC article.

9

The inhibitory function in human progesterone receptor N termini binds SUMO-1 protein to regulate autoinhibition and transrepression.

Abdel-Hafiz H, Takimoto GS, Tung L, Horwitz KB. Abdel-Hafiz H, et al. J Biol Chem. 2002 Sep 13;277(37):33950-6. doi: 10.1074/jbc.M204573200. Epub 2002 Jul 11. J Biol Chem. 2002. PMID: 12114521 Free article.

10

Functional properties of the N-terminal region of progesterone receptors and their mechanistic relationship to structure.

Takimoto GS, Tung L, Abdel-Hafiz H, Abel MG, Sartorius CA, Richer JK, Jacobsen BM, Bain DL, Horwitz KB. Takimoto GS, et al. J Steroid Biochem Mol Biol. 2003 Jun;85(2-5):209-19. doi: 10.1016/s0960-0760(03)00197-3. J Steroid Biochem Mol Biol. 2003. PMID: 12943706

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