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A strategy for liquid chromatography/tandem mass spectrometry based quantitation of pegylated protein drugs in plasma using plasma protein precipitation with water-miscible organic solvents and subsequent trypsin digestion to generate surrogate peptides for detection.
Wu ST, Ouyang Z, Olah TV, Jemal M. Wu ST, et al. Among authors: jemal m. Rapid Commun Mass Spectrom. 2011 Jan 30;25(2):281-90. doi: 10.1002/rcm.4856. Rapid Commun Mass Spectrom. 2011. PMID: 21192023
157 results