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Critical and distinct roles of p16 and telomerase in regulating the proliferative life span of normal human prostate epithelial progenitor cells.
Bhatia B, Jiang M, Suraneni M, Patrawala L, Badeaux M, Schneider-Broussard R, Multani AS, Jeter CR, Calhoun-Davis T, Hu L, Hu J, Tsavachidis S, Zhang W, Chang S, Hayward SW, Tang DG. Bhatia B, et al. Among authors: badeaux m. J Biol Chem. 2008 Oct 10;283(41):27957-27972. doi: 10.1074/jbc.M803467200. Epub 2008 Jul 28. J Biol Chem. 2008. PMID: 18662989 Free PMC article.
Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model.
Liu B, Gong S, Li Q, Chen X, Moore J, Suraneni MV, Badeaux MD, Jeter CR, Shen J, Mehmood R, Fan Q, Tang DG. Liu B, et al. Among authors: badeaux md. Oncotarget. 2017 Apr 18;8(32):52746-52760. doi: 10.18632/oncotarget.17186. eCollection 2017 Aug 8. Oncotarget. 2017. PMID: 28881767 Free PMC article.
Stress granule-associated protein G3BP2 regulates breast tumor initiation.
Gupta N, Badeaux M, Liu Y, Naxerova K, Sgroi D, Munn LL, Jain RK, Garkavtsev I. Gupta N, et al. Among authors: badeaux m. Proc Natl Acad Sci U S A. 2017 Jan 31;114(5):1033-1038. doi: 10.1073/pnas.1525387114. Epub 2017 Jan 17. Proc Natl Acad Sci U S A. 2017. PMID: 28096337 Free PMC article.
Preclinical Efficacy of Ado-trastuzumab Emtansine in the Brain Microenvironment.
Askoxylakis V, Ferraro GB, Kodack DP, Badeaux M, Shankaraiah RC, Seano G, Kloepper J, Vardam T, Martin JD, Naxerova K, Bezwada D, Qi X, Selig MK, Brachtel E, Duda DG, Huang P, Fukumura D, Engelman JA, Jain RK. Askoxylakis V, et al. Among authors: badeaux m. J Natl Cancer Inst. 2015 Nov 7;108(2):djv313. doi: 10.1093/jnci/djv313. Print 2016 Feb. J Natl Cancer Inst. 2015. PMID: 26547932 Free PMC article.
The brain microenvironment mediates resistance in luminal breast cancer to PI3K inhibition through HER3 activation.
Kodack DP, Askoxylakis V, Ferraro GB, Sheng Q, Badeaux M, Goel S, Qi X, Shankaraiah R, Cao ZA, Ramjiawan RR, Bezwada D, Patel B, Song Y, Costa C, Naxerova K, Wong CSF, Kloepper J, Das R, Tam A, Tanboon J, Duda DG, Miller CR, Siegel MB, Anders CK, Sanders M, Estrada MV, Schlegel R, Arteaga CL, Brachtel E, Huang A, Fukumura D, Engelman JA, Jain RK. Kodack DP, et al. Among authors: badeaux m. Sci Transl Med. 2017 May 24;9(391):eaal4682. doi: 10.1126/scitranslmed.aal4682. Sci Transl Med. 2017. PMID: 28539475 Free PMC article.
17 results