Hudson S - Search Results

1

Structure-activity relationships of chiral selective norepinephrine reuptake inhibitors (sNRI) with increased oxidative stability.

Hudson S, Kiankarimi M, Eccles W, Dwight W, Mostofi YS, Genicot MJ, Fleck BA, Gogas K, Aparicio A, Wang H, Wen J, Wade WS. Hudson S, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4491-4. doi: 10.1016/j.bmcl.2008.07.049. Epub 2008 Jul 17. Bioorg Med Chem Lett. 2008. PMID: 18672364

2

Synthesis and structure-activity relationships of retro bis-aminopyrrolidine urea (rAPU) derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1). Part 2.

Hudson S, Kiankarimi M, Rowbottom MW, Vickers TD, Wu D, Pontillo J, Ching B, Dwight W, Goodfellow VS, Schwarz D, Heise CE, Madan A, Wen J, Ban W, Wang H, Wade WS. Hudson S, et al. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4922-30. doi: 10.1016/j.bmcl.2006.06.049. Epub 2006 Jul 7. Bioorg Med Chem Lett. 2006. PMID: 16824755

3

Discovery of a potent, selective, and less flexible selective norepinephrine reuptake inhibitor (sNRI).

Wu D, Pontillo J, Ching B, Hudson S, Gao Y, Fleck BA, Gogas K, Wade WS. Wu D, et al. Among authors: hudson s. Bioorg Med Chem Lett. 2008 Jul 15;18(14):4224-7. doi: 10.1016/j.bmcl.2008.05.057. Epub 2008 May 20. Bioorg Med Chem Lett. 2008. PMID: 18550369

4

Synthesis and structure-activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with a heterocyclic ring constraint.

Hudson S, Kiankarimi M, Eccles W, Mostofi YS, Genicot MJ, Dwight W, Fleck BA, Gogas K, Wade WS. Hudson S, et al. Bioorg Med Chem Lett. 2008 Aug 15;18(16):4495-8. doi: 10.1016/j.bmcl.2008.07.050. Epub 2008 Jul 17. Bioorg Med Chem Lett. 2008. PMID: 18667309

5

Synthesis and structure-activity relationships of selective norepinephrine reuptake inhibitors (sNRI) with improved pharmaceutical characteristics.

Pontillo J, Wu D, Ching B, Hudson S, Genicot MJ, Gao Y, Ewing T, Fleck BA, Gogas K, Aparicio A, Wang H, Wen J, Wade WS. Pontillo J, et al. Among authors: hudson s. Bioorg Med Chem Lett. 2008 Dec 1;18(23):6151-5. doi: 10.1016/j.bmcl.2008.10.013. Epub 2008 Oct 7. Bioorg Med Chem Lett. 2008. PMID: 18954981

6

Substituted chromones and quinolones as potent melanin-concentrating hormone receptor 1 antagonists.

Dyck B, Zhao L, Tamiya J, Pontillo J, Hudson S, Ching B, Heise CE, Wen J, Norton C, Madan A, Schwarz D, Wade W, Goodfellow VS. Dyck B, et al. Among authors: hudson s. Bioorg Med Chem Lett. 2006 Aug 15;16(16):4237-42. doi: 10.1016/j.bmcl.2006.05.075. Epub 2006 Jun 12. Bioorg Med Chem Lett. 2006. PMID: 16762549

7

Pharmacological characterization of CXC chemokine receptor 3 ligands and a small molecule antagonist.

Heise CE, Pahuja A, Hudson SC, Mistry MS, Putnam AL, Gross MM, Gottlieb PA, Wade WS, Kiankarimi M, Schwarz D, Crowe P, Zlotnik A, Alleva DG. Heise CE, et al. Among authors: hudson sc. J Pharmacol Exp Ther. 2005 Jun;313(3):1263-71. doi: 10.1124/jpet.105.083683. Epub 2005 Mar 10. J Pharmacol Exp Ther. 2005. PMID: 15761110

8

A high-throughput chemotaxis assay for pharmacological characterization of chemokine receptors: Utilization of U937 monocytic cells.

Ott TR, Pahuja A, Lio FM, Mistry MS, Gross M, Hudson SC, Wade WS, Simpson PB, Struthers RS, Alleva DG. Ott TR, et al. Among authors: hudson sc. J Pharmacol Toxicol Methods. 2005 Mar-Apr;51(2):105-14. doi: 10.1016/j.vascn.2004.10.001. Epub 2004 Nov 5. J Pharmacol Toxicol Methods. 2005. PMID: 15767203

9

Strategies for the modulation of phase II metabolism in a series of PKCε inhibitors.

Clemens JJ, Coon T, Busch BB, Asgian JL, Hudson S, Termin A, Flores TB, Tran D, Chiang P, Sperry S, Gross R, Abt J, Heim R, Lechner S, Twin H, Studley J, Brenchley G, Collier PN, Pierard F, Miller A, Mak C, Dvornikovs V, Jimenez JM, Stamos D. Clemens JJ, et al. Among authors: hudson s. Bioorg Med Chem Lett. 2014 Aug 1;24(15):3398-402. doi: 10.1016/j.bmcl.2014.05.082. Epub 2014 Jun 5. Bioorg Med Chem Lett. 2014. PMID: 24939756

10

Optimization of Tubulysin Antibody-Drug Conjugates: A Case Study in Addressing ADC Metabolism.

Tumey LN, Leverett CA, Vetelino B, Li F, Rago B, Han X, Loganzo F, Musto S, Bai G, Sukuru SC, Graziani EI, Puthenveetil S, Casavant J, Ratnayake A, Marquette K, Hudson S, Doppalapudi VR, Stock J, Tchistiakova L, Bessire AJ, Clark T, Lucas J, Hosselet C, O'Donnell CJ, Subramanyam C. Tumey LN, et al. Among authors: hudson s. ACS Med Chem Lett. 2016 Jun 22;7(11):977-982. doi: 10.1021/acsmedchemlett.6b00195. eCollection 2016 Nov 10. ACS Med Chem Lett. 2016. PMID: 27882194 Free PMC article.

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