Li J - Search Results

1

Positive allosteric modulation of the alpha7 nicotinic acetylcholine receptor: ligand interactions with distinct binding sites and evidence for a prominent role of the M2-M3 segment.

Bertrand D, Bertrand S, Cassar S, Gubbins E, Li J, Gopalakrishnan M. Bertrand D, et al. Among authors: li j. Mol Pharmacol. 2008 Nov;74(5):1407-16. doi: 10.1124/mol.107.042820. Epub 2008 Aug 4. Mol Pharmacol. 2008. PMID: 18678621

2

Positive allosteric modulation of alpha7 neuronal nicotinic acetylcholine receptors: lack of cytotoxicity in PC12 cells and rat primary cortical neurons.

Hu M, Gopalakrishnan M, Li J. Hu M, et al. Among authors: li j. Br J Pharmacol. 2009 Dec;158(8):1857-64. doi: 10.1111/j.1476-5381.2009.00474.x. Br J Pharmacol. 2009. PMID: 20050184 Free PMC article.

3

Importance of M2-M3 loop in governing properties of genistein at the α7 nicotinic acetylcholine receptor inferred from α7/5-HT3A chimera.

Grønlien JH, Ween H, Thorin-Hagene K, Cassar S, Li J, Briggs CA, Gopalakrishnan M, Malysz J. Grønlien JH, et al. Among authors: li j. Eur J Pharmacol. 2010 Nov 25;647(1-3):37-47. doi: 10.1016/j.ejphar.2010.08.027. Epub 2010 Sep 9. Eur J Pharmacol. 2010. PMID: 20816816

4

Broad-spectrum efficacy across cognitive domains by alpha7 nicotinic acetylcholine receptor agonism correlates with activation of ERK1/2 and CREB phosphorylation pathways.

Bitner RS, Bunnelle WH, Anderson DJ, Briggs CA, Buccafusco J, Curzon P, Decker MW, Frost JM, Gronlien JH, Gubbins E, Li J, Malysz J, Markosyan S, Marsh K, Meyer MD, Nikkel AL, Radek RJ, Robb HM, Timmermann D, Sullivan JP, Gopalakrishnan M. Bitner RS, et al. Among authors: li j. J Neurosci. 2007 Sep 26;27(39):10578-87. doi: 10.1523/JNEUROSCI.2444-07.2007. J Neurosci. 2007. PMID: 17898229 Free PMC article.

5

Alpha7 nAChR-mediated activation of MAP kinase pathways in PC12 cells.

Gubbins EJ, Gopalakrishnan M, Li J. Gubbins EJ, et al. Among authors: li j. Brain Res. 2010 Apr 30;1328:1-11. doi: 10.1016/j.brainres.2010.02.083. Epub 2010 Mar 6. Brain Res. 2010. PMID: 20211606

6

In vitro pharmacological characterization of a novel selective alpha7 neuronal nicotinic acetylcholine receptor agonist ABT-107.

Malysz J, Anderson DJ, Grønlien JH, Ji J, Bunnelle WH, Håkerud M, Thorin-Hagene K, Ween H, Helfrich R, Hu M, Gubbins E, Gopalakrishnan S, Puttfarcken PS, Briggs CA, Li J, Meyer MD, Dyhring T, Ahring PK, Nielsen EØ, Peters D, Timmermann DB, Gopalakrishnan M. Malysz J, et al. Among authors: li j. J Pharmacol Exp Ther. 2010 Sep 1;334(3):863-74. doi: 10.1124/jpet.110.167072. Epub 2010 May 26. J Pharmacol Exp Ther. 2010. PMID: 20504915

7

Role of GSK-3beta activation and alpha7 nAChRs in Abeta(1-42)-induced tau phosphorylation in PC12 cells.

Hu M, Waring JF, Gopalakrishnan M, Li J. Hu M, et al. Among authors: li j. J Neurochem. 2008 Aug;106(3):1371-7. doi: 10.1111/j.1471-4159.2008.05483.x. Epub 2008 May 15. J Neurochem. 2008. PMID: 18485099 Free article.

8

High content screen microscopy analysis of A beta 1-42-induced neurite outgrowth reduction in rat primary cortical neurons: neuroprotective effects of alpha 7 neuronal nicotinic acetylcholine receptor ligands.

Hu M, Schurdak ME, Puttfarcken PS, El Kouhen R, Gopalakrishnan M, Li J. Hu M, et al. Among authors: li j. Brain Res. 2007 Jun 2;1151:227-35. doi: 10.1016/j.brainres.2007.03.051. Epub 2007 Mar 24. Brain Res. 2007. PMID: 17449017

9

Role of α7 nicotinic acetylcholine receptors in regulating tumor necrosis factor-α (TNF-α) as revealed by subtype selective agonists.

Li J, Mathieu SL, Harris R, Ji J, Anderson DJ, Malysz J, Bunnelle WH, Waring JF, Marsh KC, Murtaza A, Olson LM, Gopalakrishnan M. Li J, et al. J Neuroimmunol. 2011 Oct 28;239(1-2):37-43. doi: 10.1016/j.jneuroim.2011.08.007. Epub 2011 Sep 10. J Neuroimmunol. 2011. PMID: 21911260

10

Analysis of gene expression profiles in rat hippocampus following treatment with nicotine and an alpha7 nAChR selective agonist.

Waring JF, Abel S, Li J, Bitner RS, Nikkel AL, Blomme EA, Anderson DJ, Gopalakrishnan M. Waring JF, et al. Among authors: li j. Neurosci Res. 2008 Mar;60(3):266-74. doi: 10.1016/j.neures.2007.11.008. Epub 2007 Nov 22. Neurosci Res. 2008. PMID: 18164502

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