Nagata S - Search Results

1

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.

Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. Onda M, et al. Among authors: nagata s. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11311-6. doi: 10.1073/pnas.0804851105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678888 Free PMC article.

2

Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity.

Tsutsumi Y, Onda M, Nagata S, Lee B, Kreitman RJ, Pastan I. Tsutsumi Y, et al. Among authors: nagata s. Proc Natl Acad Sci U S A. 2000 Jul 18;97(15):8548-53. doi: 10.1073/pnas.140210597. Proc Natl Acad Sci U S A. 2000. PMID: 10890891 Free PMC article.

3

Inhibition of TNF-alpha produced by Kupffer cells protects against the nonspecific liver toxicity of immunotoxin anti-Tac(Fv)-PE38, LMB-2.

Onda M, Willingham M, Wang QC, Kreitman RJ, Tsutsumi Y, Nagata S, Pastan I. Onda M, et al. Among authors: nagata s. J Immunol. 2000 Dec 15;165(12):7150-6. doi: 10.4049/jimmunol.165.12.7150. J Immunol. 2000. PMID: 11120846

4

Lowering the isoelectric point of the Fv portion of recombinant immunotoxins leads to decreased nonspecific animal toxicity without affecting antitumor activity.

Onda M, Nagata S, Tsutsumi Y, Vincent JJ, Wang Q, Kreitman RJ, Lee B, Pastan I. Onda M, et al. Among authors: nagata s. Cancer Res. 2001 Jul 1;61(13):5070-7. Cancer Res. 2001. PMID: 11431343

5

Generation and characterization of novel monoclonal antibodies to the Ret receptor tyrosine kinase.

Salvatore G, Nagata S, Billaud M, Santoro M, Vecchio G, Pastan I. Salvatore G, et al. Among authors: nagata s. Biochem Biophys Res Commun. 2002 Jun 21;294(4):813-7. doi: 10.1016/S0006-291X(02)00560-0. Biochem Biophys Res Commun. 2002. PMID: 12061779

6

Novel anti-CD30 recombinant immunotoxins containing disulfide-stabilized Fv fragments.

Nagata S, Onda M, Numata Y, Santora K, Beers R, Kreitman RJ, Pastan I. Nagata S, et al. Clin Cancer Res. 2002 Jul;8(7):2345-55. Clin Cancer Res. 2002. PMID: 12114439

7

DNA immunization followed by a single boost with cells: a protein-free immunization protocol for production of monoclonal antibodies against the native form of membrane proteins.

Nagata S, Salvatore G, Pastan I. Nagata S, et al. J Immunol Methods. 2003 Sep;280(1-2):59-72. doi: 10.1016/s0022-1759(03)00192-3. J Immunol Methods. 2003. PMID: 12972188

8

The T cell receptor gamma chain alternate reading frame protein (TARP), a prostate-specific protein localized in mitochondria.

Maeda H, Nagata S, Wolfgang CD, Bratthauer GL, Bera TK, Pastan I. Maeda H, et al. Among authors: nagata s. J Biol Chem. 2004 Jun 4;279(23):24561-8. doi: 10.1074/jbc.M402492200. Epub 2004 Mar 29. J Biol Chem. 2004. PMID: 15150260 Free article.

9

Rapid grouping of monoclonal antibodies based on their topographical epitopes by a label-free competitive immunoassay.

Nagata S, Numata Y, Onda M, Ise T, Hahn Y, Lee B, Pastan I. Nagata S, et al. J Immunol Methods. 2004 Sep;292(1-2):141-55. doi: 10.1016/j.jim.2004.06.009. J Immunol Methods. 2004. PMID: 15350519

10

Immunoglobulin superfamily receptor translocation associated 2 protein on lymphoma cell lines and hairy cell leukemia cells detected by novel monoclonal antibodies.

Ise T, Maeda H, Santora K, Xiang L, Kreitman RJ, Pastan I, Nagata S. Ise T, et al. Among authors: nagata s. Clin Cancer Res. 2005 Jan 1;11(1):87-96. Clin Cancer Res. 2005. PMID: 15671532

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