Xiang L - Search Results

1

An immunotoxin with greatly reduced immunogenicity by identification and removal of B cell epitopes.

Onda M, Beers R, Xiang L, Nagata S, Wang QC, Pastan I. Onda M, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2008 Aug 12;105(32):11311-6. doi: 10.1073/pnas.0804851105. Epub 2008 Aug 4. Proc Natl Acad Sci U S A. 2008. PMID: 18678888 Free PMC article.

2

Immunotoxin and Taxol synergy results from a decrease in shed mesothelin levels in the extracellular space of tumors.

Zhang Y, Xiang L, Hassan R, Pastan I. Zhang Y, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2007 Oct 23;104(43):17099-104. doi: 10.1073/pnas.0708101104. Epub 2007 Oct 16. Proc Natl Acad Sci U S A. 2007. PMID: 17940013 Free PMC article.

3

A protease-resistant immunotoxin against CD22 with greatly increased activity against CLL and diminished animal toxicity.

Weldon JE, Xiang L, Chertov O, Margulies I, Kreitman RJ, FitzGerald DJ, Pastan I. Weldon JE, et al. Among authors: xiang l. Blood. 2009 Apr 16;113(16):3792-800. doi: 10.1182/blood-2008-08-173195. Epub 2008 Nov 6. Blood. 2009. PMID: 18988862 Free PMC article.

4

A recombinant immunotoxin targeting CD22 with low immunogenicity, low nonspecific toxicity, and high antitumor activity in mice.

Hansen JK, Weldon JE, Xiang L, Beers R, Onda M, Pastan I. Hansen JK, et al. Among authors: xiang l. J Immunother. 2010 Apr;33(3):297-304. doi: 10.1097/CJI.0b013e3181cd1164. J Immunother. 2010. PMID: 20445350 Free PMC article.

5

Recombinant immunotoxin against B-cell malignancies with no immunogenicity in mice by removal of B-cell epitopes.

Onda M, Beers R, Xiang L, Lee B, Weldon JE, Kreitman RJ, Pastan I. Onda M, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2011 Apr 5;108(14):5742-7. doi: 10.1073/pnas.1102746108. Epub 2011 Mar 21. Proc Natl Acad Sci U S A. 2011. PMID: 21436054 Free PMC article.

6

A recombinant immunotoxin engineered for increased stability by adding a disulfide bond has decreased immunogenicity.

Liu W, Onda M, Kim C, Xiang L, Weldon JE, Lee B, Pastan I. Liu W, et al. Among authors: xiang l. Protein Eng Des Sel. 2012 Jan;25(1):1-6. doi: 10.1093/protein/gzr053. Epub 2011 Nov 17. Protein Eng Des Sel. 2012. PMID: 22101015 Free PMC article.

7

Immunotoxin resistance via reversible methylation of the DPH4 promoter is a unique survival strategy.

Wei H, Xiang L, Wayne AS, Chertov O, FitzGerald DJ, Bera TK, Pastan I. Wei H, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2012 May 1;109(18):6898-903. doi: 10.1073/pnas.1204523109. Epub 2012 Apr 16. Proc Natl Acad Sci U S A. 2012. PMID: 22509046 Free PMC article.

8

Recombinant immunotoxin engineered for low immunogenicity and antigenicity by identifying and silencing human B-cell epitopes.

Liu W, Onda M, Lee B, Kreitman RJ, Hassan R, Xiang L, Pastan I. Liu W, et al. Among authors: xiang l. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11782-7. doi: 10.1073/pnas.1209292109. Epub 2012 Jul 2. Proc Natl Acad Sci U S A. 2012. PMID: 22753489 Free PMC article.

9

A recombinant immunotoxin against the tumor-associated antigen mesothelin reengineered for high activity, low off-target toxicity, and reduced antigenicity.

Weldon JE, Xiang L, Zhang J, Beers R, Walker DA, Onda M, Hassan R, Pastan I. Weldon JE, et al. Among authors: xiang l. Mol Cancer Ther. 2013 Jan;12(1):48-57. doi: 10.1158/1535-7163.MCT-12-0336. Epub 2012 Nov 6. Mol Cancer Ther. 2013. PMID: 23136186 Free PMC article.

10

Recombinant Immunotoxin with T-cell Epitope Mutations That Greatly Reduce Immunogenicity for Treatment of Mesothelin-Expressing Tumors.

Mazor R, Zhang J, Xiang L, Addissie S, Awuah P, Beers R, Hassan R, Pastan I. Mazor R, et al. Among authors: xiang l. Mol Cancer Ther. 2015 Dec;14(12):2789-96. doi: 10.1158/1535-7163.MCT-15-0532. Epub 2015 Oct 6. Mol Cancer Ther. 2015. PMID: 26443804 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My Custom Filters

Publication date

Text availability

Article attribute

Article type

Article Language

Species

Sex

Age

Other

3,490 results

Search Page

Filters