Ilieva H - Search Results

1

Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.

Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Chang Y, et al. Among authors: ilieva h. PLoS One. 2008 Aug 6;3(8):e2849. doi: 10.1371/journal.pone.0002849. PLoS One. 2008. PMID: 18682740 Free PMC article.

2

Non-cell autonomous toxicity in neurodegenerative disorders: ALS and beyond.

Ilieva H, Polymenidou M, Cleveland DW. Ilieva H, et al. J Cell Biol. 2009 Dec 14;187(6):761-72. doi: 10.1083/jcb.200908164. J Cell Biol. 2009. PMID: 19951898 Free PMC article. Review.

3

Therapeutic AAV9-mediated suppression of mutant SOD1 slows disease progression and extends survival in models of inherited ALS.

Foust KD, Salazar DL, Likhite S, Ferraiuolo L, Ditsworth D, Ilieva H, Meyer K, Schmelzer L, Braun L, Cleveland DW, Kaspar BK. Foust KD, et al. Among authors: ilieva h. Mol Ther. 2013 Dec;21(12):2148-59. doi: 10.1038/mt.2013.211. Epub 2013 Sep 6. Mol Ther. 2013. PMID: 24008656 Free PMC article.

4

Mutant dynein (Loa) triggers proprioceptive axon loss that extends survival only in the SOD1 ALS model with highest motor neuron death.

Ilieva HS, Yamanaka K, Malkmus S, Kakinohana O, Yaksh T, Marsala M, Cleveland DW. Ilieva HS, et al. Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12599-604. doi: 10.1073/pnas.0805422105. Epub 2008 Aug 21. Proc Natl Acad Sci U S A. 2008. PMID: 18719118 Free PMC article.

5

Activated protein C therapy slows ALS-like disease in mice by transcriptionally inhibiting SOD1 in motor neurons and microglia cells.

Zhong Z, Ilieva H, Hallagan L, Bell R, Singh I, Paquette N, Thiyagarajan M, Deane R, Fernandez JA, Lane S, Zlokovic AB, Liu T, Griffin JH, Chow N, Castellino FJ, Stojanovic K, Cleveland DW, Zlokovic BV. Zhong Z, et al. Among authors: ilieva h. J Clin Invest. 2009 Nov;119(11):3437-49. doi: 10.1172/JCI38476. Epub 2009 Oct 19. J Clin Invest. 2009. PMID: 19841542 Free PMC article.

6

Misfolded mutant SOD1 directly inhibits VDAC1 conductance in a mouse model of inherited ALS.

Israelson A, Arbel N, Da Cruz S, Ilieva H, Yamanaka K, Shoshan-Barmatz V, Cleveland DW. Israelson A, et al. Among authors: ilieva h. Neuron. 2010 Aug 26;67(4):575-87. doi: 10.1016/j.neuron.2010.07.019. Neuron. 2010. PMID: 20797535 Free PMC article.

7

Overriding FUS autoregulation in mice triggers gain-of-toxic dysfunctions in RNA metabolism and autophagy-lysosome axis.

Ling SC, Dastidar SG, Tokunaga S, Ho WY, Lim K, Ilieva H, Parone PA, Tyan SH, Tse TM, Chang JC, Platoshyn O, Bui NB, Bui A, Vetto A, Sun S, McAlonis-Downes M, Han JS, Swing D, Kapeli K, Yeo GW, Tessarollo L, Marsala M, Shaw CE, Tucker-Kellogg G, La Spada AR, Lagier-Tourenne C, Da Cruz S, Cleveland DW. Ling SC, et al. Among authors: ilieva h. Elife. 2019 Feb 12;8:e40811. doi: 10.7554/eLife.40811. Elife. 2019. PMID: 30747709 Free PMC article.

8

Increased synthesis of pro-inflammatory cytokines in C9ORF72 patients.

Pinilla G, Kumar A, Floaters MK, Pardo CA, Rothstein J, Ilieva H. Pinilla G, et al. Among authors: ilieva h. Amyotroph Lateral Scler Frontotemporal Degener. 2021 Nov;22(7-8):517-527. doi: 10.1080/21678421.2021.1912100. Epub 2021 Apr 30. Amyotroph Lateral Scler Frontotemporal Degener. 2021. PMID: 33929933

9

Increased ER stress during motor neuron degeneration in a transgenic mouse model of amyotrophic lateral sclerosis.

Nagata T, Ilieva H, Murakami T, Shiote M, Narai H, Ohta Y, Hayashi T, Shoji M, Abe K. Nagata T, et al. Among authors: ilieva h. Neurol Res. 2007 Dec;29(8):767-71. doi: 10.1179/016164107X229803. Neurol Res. 2007. PMID: 17672929

10

Mitochondria-associated membrane collapse is a common pathomechanism in SIGMAR1- and SOD1-linked ALS.

Watanabe S, Ilieva H, Tamada H, Nomura H, Komine O, Endo F, Jin S, Mancias P, Kiyama H, Yamanaka K. Watanabe S, et al. Among authors: ilieva h. EMBO Mol Med. 2016 Dec 1;8(12):1421-1437. doi: 10.15252/emmm.201606403. Print 2016 Dec. EMBO Mol Med. 2016. PMID: 27821430 Free PMC article.

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