Rothstein JD - Search Results

1

Messenger RNA oxidation occurs early in disease pathogenesis and promotes motor neuron degeneration in ALS.

Chang Y, Kong Q, Shan X, Tian G, Ilieva H, Cleveland DW, Rothstein JD, Borchelt DR, Wong PC, Lin CL. Chang Y, et al. Among authors: rothstein jd. PLoS One. 2008 Aug 6;3(8):e2849. doi: 10.1371/journal.pone.0002849. PLoS One. 2008. PMID: 18682740 Free PMC article.

2

ALS-linked SOD1 mutant G85R mediates damage to astrocytes and promotes rapidly progressive disease with SOD1-containing inclusions.

Bruijn LI, Becher MW, Lee MK, Anderson KL, Jenkins NA, Copeland NG, Sisodia SS, Rothstein JD, Borchelt DR, Price DL, Cleveland DW. Bruijn LI, et al. Among authors: rothstein jd. Neuron. 1997 Feb;18(2):327-38. doi: 10.1016/s0896-6273(00)80272-x. Neuron. 1997. PMID: 9052802 Free article.

3

The copper chaperone CCS is abundant in neurons and astrocytes in human and rodent brain.

Rothstein JD, Dykes-Hoberg M, Corson LB, Becker M, Cleveland DW, Price DL, Culotta VC, Wong PC. Rothstein JD, et al. J Neurochem. 1999 Jan;72(1):422-9. doi: 10.1046/j.1471-4159.1999.0720422.x. J Neurochem. 1999. PMID: 9886096 Free article.

4

The genetic and molecular mechanisms of motor neuron disease.

Wong PC, Rothstein JD, Price DL. Wong PC, et al. Among authors: rothstein jd. Curr Opin Neurobiol. 1998 Dec;8(6):791-9. doi: 10.1016/s0959-4388(98)80123-2. Curr Opin Neurobiol. 1998. PMID: 9914243 Review.

5

From Charcot to Lou Gehrig: deciphering selective motor neuron death in ALS.

Cleveland DW, Rothstein JD. Cleveland DW, et al. Among authors: rothstein jd. Nat Rev Neurosci. 2001 Nov;2(11):806-19. doi: 10.1038/35097565. Nat Rev Neurosci. 2001. PMID: 11715057 Review. No abstract available.

6

Histological evidence of protein aggregation in mutant SOD1 transgenic mice and in amyotrophic lateral sclerosis neural tissues.

Watanabe M, Dykes-Hoberg M, Culotta VC, Price DL, Wong PC, Rothstein JD. Watanabe M, et al. Among authors: rothstein jd. Neurobiol Dis. 2001 Dec;8(6):933-41. doi: 10.1006/nbdi.2001.0443. Neurobiol Dis. 2001. PMID: 11741389

7

Focal loss of the glutamate transporter EAAT2 in a transgenic rat model of SOD1 mutant-mediated amyotrophic lateral sclerosis (ALS).

Howland DS, Liu J, She Y, Goad B, Maragakis NJ, Kim B, Erickson J, Kulik J, DeVito L, Psaltis G, DeGennaro LJ, Cleveland DW, Rothstein JD. Howland DS, et al. Among authors: rothstein jd. Proc Natl Acad Sci U S A. 2002 Feb 5;99(3):1604-9. doi: 10.1073/pnas.032539299. Epub 2002 Jan 29. Proc Natl Acad Sci U S A. 2002. PMID: 11818550 Free PMC article.

8

Amyotrophic lateral sclerosis 2-deficiency leads to neuronal degeneration in amyotrophic lateral sclerosis through altered AMPA receptor trafficking.

Lai C, Xie C, McCormack SG, Chiang HC, Michalak MK, Lin X, Chandran J, Shim H, Shimoji M, Cookson MR, Huganir RL, Rothstein JD, Price DL, Wong PC, Martin LJ, Zhu JJ, Cai H. Lai C, et al. Among authors: rothstein jd. J Neurosci. 2006 Nov 8;26(45):11798-806. doi: 10.1523/JNEUROSCI.2084-06.2006. J Neurosci. 2006. PMID: 17093100 Free PMC article.

9

Motor neuron disease occurring in a mutant dynactin mouse model is characterized by defects in vesicular trafficking.

Laird FM, Farah MH, Ackerley S, Hoke A, Maragakis N, Rothstein JD, Griffin J, Price DL, Martin LJ, Wong PC. Laird FM, et al. Among authors: rothstein jd. J Neurosci. 2008 Feb 27;28(9):1997-2005. doi: 10.1523/JNEUROSCI.4231-07.2008. J Neurosci. 2008. PMID: 18305234 Free PMC article.

10

Degeneration and impaired regeneration of gray matter oligodendrocytes in amyotrophic lateral sclerosis.

Kang SH, Li Y, Fukaya M, Lorenzini I, Cleveland DW, Ostrow LW, Rothstein JD, Bergles DE. Kang SH, et al. Among authors: rothstein jd. Nat Neurosci. 2013 May;16(5):571-9. doi: 10.1038/nn.3357. Epub 2013 Mar 31. Nat Neurosci. 2013. PMID: 23542689 Free PMC article.

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