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Page 1
A new map of glycosaminoglycan and C3b binding sites on factor H.
Schmidt CQ, Herbert AP, Kavanagh D, Gandy C, Fenton CJ, Blaum BS, Lyon M, Uhrín D, Barlow PN. Schmidt CQ, et al. Among authors: blaum bs. J Immunol. 2008 Aug 15;181(4):2610-9. doi: 10.4049/jimmunol.181.4.2610. J Immunol. 2008. PMID: 18684951
Structure shows that a glycosaminoglycan and protein recognition site in factor H is perturbed by age-related macular degeneration-linked single nucleotide polymorphism.
Herbert AP, Deakin JA, Schmidt CQ, Blaum BS, Egan C, Ferreira VP, Pangburn MK, Lyon M, Uhrín D, Barlow PN. Herbert AP, et al. Among authors: blaum bs. J Biol Chem. 2007 Jun 29;282(26):18960-8. doi: 10.1074/jbc.M609636200. Epub 2007 Mar 13. J Biol Chem. 2007. PMID: 17360715 Free article.
Structural basis for engagement by complement factor H of C3b on a self surface.
Morgan HP, Schmidt CQ, Guariento M, Blaum BS, Gillespie D, Herbert AP, Kavanagh D, Mertens HD, Svergun DI, Johansson CM, Uhrín D, Barlow PN, Hannan JP. Morgan HP, et al. Among authors: blaum bs. Nat Struct Mol Biol. 2011 Apr;18(4):463-70. doi: 10.1038/nsmb.2018. Epub 2011 Feb 13. Nat Struct Mol Biol. 2011. PMID: 21317894 Free PMC article.
Structural basis for complement factor H linked age-related macular degeneration.
Prosser BE, Johnson S, Roversi P, Herbert AP, Blaum BS, Tyrrell J, Jowitt TA, Clark SJ, Tarelli E, Uhrín D, Barlow PN, Sim RB, Day AJ, Lea SM. Prosser BE, et al. Among authors: blaum bs. J Exp Med. 2007 Oct 1;204(10):2277-83. doi: 10.1084/jem.20071069. Epub 2007 Sep 24. J Exp Med. 2007. PMID: 17893204 Free PMC article.
Interaction of human β-defensin 2 (HBD2) with glycosaminoglycans.
Seo ES, Blaum BS, Vargues T, De Cecco M, Deakin JA, Lyon M, Barran PE, Campopiano DJ, Uhrín D. Seo ES, et al. Among authors: blaum bs. Biochemistry. 2010 Dec 14;49(49):10486-95. doi: 10.1021/bi1011749. Epub 2010 Nov 17. Biochemistry. 2010. PMID: 21062008
34 results