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Enhanced mitochondrial G-quadruplex formation impedes replication fork progression leading to mtDNA loss in human cells.
Doimo M, Chaudhari N, Abrahamsson S, L'Hôte V, Nguyen TVH, Berner A, Ndi M, Abrahamsson A, Das RN, Aasumets K, Goffart S, Pohjoismäki JLO, López MD, Chorell E, Wanrooij S. Doimo M, et al. Among authors: wanrooij s. Nucleic Acids Res. 2023 Aug 11;51(14):7392-7408. doi: 10.1093/nar/gkad535. Nucleic Acids Res. 2023. PMID: 37351621 Free PMC article.
Oxidative DNA damage stalls the human mitochondrial replisome.
Stojkovič G, Makarova AV, Wanrooij PH, Forslund J, Burgers PM, Wanrooij S. Stojkovič G, et al. Among authors: wanrooij s, wanrooij ph. Sci Rep. 2016 Jul 1;6:28942. doi: 10.1038/srep28942. Sci Rep. 2016. PMID: 27364318 Free PMC article.
42 results