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Synthesis and biological evaluation of novel pyrazoles and indazoles as activators of the nitric oxide receptor, soluble guanylate cyclase.
Selwood DL, Brummell DG, Budworth J, Burtin GE, Campbell RO, Chana SS, Charles IG, Fernandez PA, Glen RC, Goggin MC, Hobbs AJ, Kling MR, Liu Q, Madge DJ, Meillerais S, Powell KL, Reynolds K, Spacey GD, Stables JN, Tatlock MA, Wheeler KA, Wishart G, Woo CK. Selwood DL, et al. J Med Chem. 2001 Jan 4;44(1):78-93. doi: 10.1021/jm001034k. J Med Chem. 2001. PMID: 11141091
Disruption of methylarginine metabolism impairs vascular homeostasis.
Leiper J, Nandi M, Torondel B, Murray-Rust J, Malaki M, O'Hara B, Rossiter S, Anthony S, Madhani M, Selwood D, Smith C, Wojciak-Stothard B, Rudiger A, Stidwill R, McDonald NQ, Vallance P. Leiper J, et al. Among authors: selwood d. Nat Med. 2007 Feb;13(2):198-203. doi: 10.1038/nm1543. Epub 2007 Feb 4. Nat Med. 2007. PMID: 17273169 Free article.
Exploring the interaction between siRNA and the SMoC biomolecule transporters: implications for small molecule-mediated delivery of siRNA.
Gooding M, Tudzarova S, Worthington RJ, Kingsbury SR, Rebstock AS, Dube H, Simone MI, Visintin C, Lagos D, Quesada JM, Laman H, Boshoff C, Williams GH, Stoeber K, Selwood DL. Gooding M, et al. Among authors: selwood dl. Chem Biol Drug Des. 2012 Jan;79(1):9-21. doi: 10.1111/j.1747-0285.2011.01249.x. Epub 2011 Nov 4. Chem Biol Drug Des. 2012. PMID: 21981778
Control of spasticity in a multiple sclerosis model using central nervous system-excluded CB1 cannabinoid receptor agonists.
Pryce G, Visintin C, Ramagopalan SV, Al-Izki S, De Faveri LE, Nuamah RA, Mein CA, Montpetit A, Hardcastle AJ, Kooij G, de Vries HE, Amor S, Thomas SA, Ledent C, Marsicano G, Lutz B, Thompson AJ, Selwood DL, Giovannoni G, Baker D. Pryce G, et al. Among authors: selwood dl. FASEB J. 2014 Jan;28(1):117-30. doi: 10.1096/fj.13-239442. Epub 2013 Oct 11. FASEB J. 2014. PMID: 24121462
94 results