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Page 1
Old and new targets for innovative antimalarial compounds: the different strategies of the Italian Malaria Network.
Basilico N, Bosisio E, Buelli F, Campiani G, Casagrande M, Castelli F, Coghi P, Corbett Y, Cortelezzi L, D'Alessandro S, Dell'Agli M, Esposito F, Fattorusso C, Fattorusso E, Finaurini S, Galli GV, Gemma S, Habluetzel A, Lucantoni L, Melato S, Monti D, Olliaro P, Omodeo-Salè F, Parapini S, Persico M, Rizzi M, Romeo S, Rossi F, Rusconi C, Sparatore A, Scafati OT, van den Bogaart E, Taramelli D, Vaiana N, Yerbanga S. Basilico N, et al. Among authors: persico m. Parassitologia. 2008 Jun;50(1-2):133-6. Parassitologia. 2008. PMID: 18693579
Development of molecular probes for the identification of extra interaction sites in the mid-gorge and peripheral sites of butyrylcholinesterase (BuChE). Rational design of novel, selective, and highly potent BuChE inhibitors.
Campiani G, Fattorusso C, Butini S, Gaeta A, Agnusdei M, Gemma S, Persico M, Catalanotti B, Savini L, Nacci V, Novellino E, Holloway HW, Greig NH, Belinskaya T, Fedorko JM, Saxena A. Campiani G, et al. Among authors: persico m. J Med Chem. 2005 Mar 24;48(6):1919-29. doi: 10.1021/jm049510k. J Med Chem. 2005. PMID: 15771436
Specific targeting highly conserved residues in the HIV-1 reverse transcriptase primer grip region. Design, synthesis, and biological evaluation of novel, potent, and broad spectrum NNRTIs with antiviral activity.
Fattorusso C, Gemma S, Butini S, Huleatt P, Catalanotti B, Persico M, De Angelis M, Fiorini I, Nacci V, Ramunno A, Rodriquez M, Greco G, Novellino E, Bergamini A, Marini S, Coletta M, Maga G, Spadari S, Campiani G. Fattorusso C, et al. Among authors: persico m. J Med Chem. 2005 Nov 17;48(23):7153-65. doi: 10.1021/jm050257d. J Med Chem. 2005. PMID: 16279773
Synthesis of N1-arylidene-N2-quinolyl- and N2-acrydinylhydrazones as potent antimalarial agents active against CQ-resistant P. falciparum strains.
Gemma S, Kukreja G, Fattorusso C, Persico M, Romano MP, Altarelli M, Savini L, Campiani G, Fattorusso E, Basilico N, Taramelli D, Yardley V, Butini S. Gemma S, et al. Among authors: persico m. Bioorg Med Chem Lett. 2006 Oct 15;16(20):5384-8. doi: 10.1016/j.bmcl.2006.07.060. Epub 2006 Aug 4. Bioorg Med Chem Lett. 2006. PMID: 16890433
Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore.
Gemma S, Campiani G, Butini S, Kukreja G, Joshi BP, Persico M, Catalanotti B, Novellino E, Fattorusso E, Nacci V, Savini L, Taramelli D, Basilico N, Morace G, Yardley V, Fattorusso C. Gemma S, et al. Among authors: persico m. J Med Chem. 2007 Feb 22;50(4):595-8. doi: 10.1021/jm061429p. Epub 2007 Jan 31. J Med Chem. 2007. PMID: 17263523
Development of piperazine-tethered heterodimers as potent antimalarials against chloroquine-resistant P. falciparum strains. Synthesis and molecular modeling.
Gemma S, Kukreja G, Campiani G, Butini S, Bernetti M, Joshi BP, Savini L, Basilico N, Taramelli D, Yardley V, Bertamino A, Novellino E, Persico M, Catalanotti B, Fattorusso C. Gemma S, et al. Among authors: persico m. Bioorg Med Chem Lett. 2007 Jul 1;17(13):3535-9. doi: 10.1016/j.bmcl.2007.04.077. Epub 2007 Apr 29. Bioorg Med Chem Lett. 2007. PMID: 17493808
Design, synthesis, and structure-activity relationship studies of 4-quinolinyl- and 9-acrydinylhydrazones as potent antimalarial agents.
Fattorusso C, Campiani G, Kukreja G, Persico M, Butini S, Romano MP, Altarelli M, Ros S, Brindisi M, Savini L, Novellino E, Nacci V, Fattorusso E, Parapini S, Basilico N, Taramelli D, Yardley V, Croft S, Borriello M, Gemma S. Fattorusso C, et al. Among authors: persico m. J Med Chem. 2008 Mar 13;51(5):1333-43. doi: 10.1021/jm7012375. Epub 2008 Feb 16. J Med Chem. 2008. PMID: 18278859
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies.
Gemma S, Campiani G, Butini S, Kukreja G, Coccone SS, Joshi BP, Persico M, Nacci V, Fiorini I, Novellino E, Fattorusso E, Taglialatela-Scafati O, Savini L, Taramelli D, Basilico N, Parapini S, Morace G, Yardley V, Croft S, Coletta M, Marini S, Fattorusso C. Gemma S, et al. Among authors: persico m. J Med Chem. 2008 Mar 13;51(5):1278-94. doi: 10.1021/jm701247k. Epub 2008 Feb 16. J Med Chem. 2008. PMID: 18278860 Free article.
512 results