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Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE. Michailidou Z, et al. FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12. FASEB J. 2008. PMID: 18697839 Free PMC article.
Cyp11b1 null mouse, a model of congenital adrenal hyperplasia.
Mullins LJ, Peter A, Wrobel N, McNeilly JR, McNeilly AS, Al-Dujaili EA, Brownstein DG, Mullins JJ, Kenyon CJ. Mullins LJ, et al. J Biol Chem. 2009 Feb 6;284(6):3925-34. doi: 10.1074/jbc.M805081200. Epub 2008 Nov 24. J Biol Chem. 2009. PMID: 19029289 Free article.
Conditional Deletion of Hsd11b2 in the Brain Causes Salt Appetite and Hypertension.
Evans LC, Ivy JR, Wyrwoll C, McNairn JA, Menzies RI, Christensen TH, Al-Dujaili EA, Kenyon CJ, Mullins JJ, Seckl JR, Holmes MC, Bailey MA. Evans LC, et al. Circulation. 2016 Apr 5;133(14):1360-70. doi: 10.1161/CIRCULATIONAHA.115.019341. Epub 2016 Mar 7. Circulation. 2016. PMID: 26951843 Free PMC article.
81 results