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Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE. Michailidou Z, et al. Among authors: cockett k. FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12. FASEB J. 2008. PMID: 18697839 Free PMC article.