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Glucocorticoid receptor haploinsufficiency causes hypertension and attenuates hypothalamic-pituitary-adrenal axis and blood pressure adaptions to high-fat diet.
Michailidou Z, Carter RN, Marshall E, Sutherland HG, Brownstein DG, Owen E, Cockett K, Kelly V, Ramage L, Al-Dujaili EA, Ross M, Maraki I, Newton K, Holmes MC, Seckl JR, Morton NM, Kenyon CJ, Chapman KE. Michailidou Z, et al. FASEB J. 2008 Nov;22(11):3896-907. doi: 10.1096/fj.08-111914. Epub 2008 Aug 12. FASEB J. 2008. PMID: 18697839 Free PMC article.
Glucocorticoid receptor is required for foetal heart maturation.
Rog-Zielinska EA, Thomson A, Kenyon CJ, Brownstein DG, Moran CM, Szumska D, Michailidou Z, Richardson J, Owen E, Watt A, Morrison H, Forrester LM, Bhattacharya S, Holmes MC, Chapman KE. Rog-Zielinska EA, et al. Among authors: michailidou z. Hum Mol Genet. 2013 Aug 15;22(16):3269-82. doi: 10.1093/hmg/ddt182. Epub 2013 Apr 16. Hum Mol Genet. 2013. PMID: 23595884
21 results