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Synthesis, antimalarial activity, and intracellular targets of MEFAS, a new hybrid compound derived from mefloquine and artesunate.
de Pilla Varotti F, Botelho AC, Andrade AA, de Paula RC, Fagundes EM, Valverde A, Mayer LM, Mendonça JS, de Souza MV, Boechat N, Krettli AU. de Pilla Varotti F, et al. Among authors: boechat n. Antimicrob Agents Chemother. 2008 Nov;52(11):3868-74. doi: 10.1128/AAC.00510-08. Epub 2008 Aug 18. Antimicrob Agents Chemother. 2008. PMID: 18710907 Free PMC article.
In vitro evaluation of 2-(1H-pyrazol-1-yl)-1,3,4-thiadiazole derivatives against replicative and infective stages of Trypanosoma cruzi.
Faria AFM, de Souza Ferreira Pereira C, Teixeira GP, Dos Santos Galvão RM, Pacheco PAF, Bello ML, de Jesus DH, Calabrese K, Gonzaga DTG, Boechat N, Faria RX. Faria AFM, et al. Among authors: boechat n. J Bioenerg Biomembr. 2023 Dec;55(6):409-421. doi: 10.1007/s10863-023-09982-7. Epub 2023 Nov 3. J Bioenerg Biomembr. 2023. PMID: 37919636
In silico and in vitro assessment of anti-Trypanosoma cruzi efficacy, genotoxicity and pharmacokinetics of pentasubstituted pyrrolic Atorvastatin-aminoquinoline hybrid compounds.
Araujo-Lima CF, Carvalho RCC, Peres RB, Fiuza LFA, Galvão BVD, Castelo-Branco FS, Bastos MM, Boechat N, Felzenszwalb I, Soeiro MNC. Araujo-Lima CF, et al. Among authors: boechat n. Acta Trop. 2023 Jun;242:106924. doi: 10.1016/j.actatropica.2023.106924. Epub 2023 Apr 8. Acta Trop. 2023. PMID: 37037291
Hydrogen-bonded chains in 5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one and hydrogen-bonded chains of rings in 5-amino-3-trifluoromethyl-1H-1,2,4-triazole-5-methyl-2-trifluoromethyl-1,2,4-triazolo[1,5-a]pyrimidin-7(4H)-one (1/1), the co-crystal of a reaction product and one of its precursors.
Boechat N, Dutra KD, Valverde AL, Wardell SM, Low JN, Glidewell C. Boechat N, et al. Acta Crystallogr C. 2004 Oct;60(Pt 10):o733-6. doi: 10.1107/S0108270104020256. Epub 2004 Sep 18. Acta Crystallogr C. 2004. PMID: 15467144 No abstract available.
In vitro and in vivo activity of meglumine antimoniate produced at Farmanguinhos-Fiocruz, Brazil, against Leishmania (Leishmania) amazonensis, L (L.) chagasi and L (Viannia) braziliensis.
Morais-Teixeira Ed, Carvalho AS, Costa JC, Duarte SL, Mendonça JS, Boechat N, Rabello A. Morais-Teixeira Ed, et al. Among authors: boechat n. Mem Inst Oswaldo Cruz. 2008 Jun;103(4):358-62. doi: 10.1590/s0074-02762008000400008. Mem Inst Oswaldo Cruz. 2008. PMID: 18660990 Free article.
124 results