Rosen N - Search Results

1

Breast tumor cells with PI3K mutation or HER2 amplification are selectively addicted to Akt signaling.

She QB, Chandarlapaty S, Ye Q, Lobo J, Haskell KM, Leander KR, DeFeo-Jones D, Huber HE, Rosen N. She QB, et al. Among authors: rosen n. PLoS One. 2008 Aug 26;3(8):e3065. doi: 10.1371/journal.pone.0003065. PLoS One. 2008. PMID: 18725974 Free PMC article.

2

Insulin-like growth factors modulate the growth inhibitory effects of retinoic acid on MCF-7 breast cancer cells.

Bentel JM, Lebwohl DE, Cullen KJ, Rubin MS, Rosen N, Mendelsohn J, Miller WH Jr. Bentel JM, et al. Among authors: rosen n. J Cell Physiol. 1995 Oct;165(1):212-21. doi: 10.1002/jcp.1041650124. J Cell Physiol. 1995. PMID: 7559803

3

Insulin and insulin-like growth factor signaling are defective in the MDA MB-468 human breast cancer cell line.

Sepp-Lorenzino L, Rosen N, Lebwohl DE. Sepp-Lorenzino L, et al. Among authors: rosen n. Cell Growth Differ. 1994 Oct;5(10):1077-83. Cell Growth Differ. 1994. PMID: 7848909

4

Signal transduction pathways induced by heregulin in MDA-MB-453 breast cancer cells.

Sepp-Lorenzino L, Eberhard I, Ma Z, Cho C, Serve H, Liu F, Rosen N, Lupu R. Sepp-Lorenzino L, et al. Among authors: rosen n. Oncogene. 1996 Apr 18;12(8):1679-87. Oncogene. 1996. PMID: 8622888

5

A farnesyl-protein transferase inhibitor induces p21 expression and G1 block in p53 wild type tumor cells.

Sepp-Lorenzino L, Rosen N. Sepp-Lorenzino L, et al. Among authors: rosen n. J Biol Chem. 1998 Aug 7;273(32):20243-51. doi: 10.1074/jbc.273.32.20243. J Biol Chem. 1998. PMID: 9685373 Free article.

6

Identification of a geldanamycin dimer that induces the selective degradation of HER-family tyrosine kinases.

Zheng FF, Kuduk SD, Chiosis G, Münster PN, Sepp-Lorenzino L, Danishefsky SJ, Rosen N. Zheng FF, et al. Among authors: rosen n. Cancer Res. 2000 Apr 15;60(8):2090-4. Cancer Res. 2000. PMID: 10786665

7

Inhibition of Hsp90 function by ansamycins causes retinoblastoma gene product-dependent G1 arrest.

Srethapakdi M, Liu F, Tavorath R, Rosen N. Srethapakdi M, et al. Among authors: rosen n. Cancer Res. 2000 Jul 15;60(14):3940-6. Cancer Res. 2000. PMID: 10919672

8

A small molecule designed to bind to the adenine nucleotide pocket of Hsp90 causes Her2 degradation and the growth arrest and differentiation of breast cancer cells.

Chiosis G, Timaul MN, Lucas B, Munster PN, Zheng FF, Sepp-Lorenzino L, Rosen N. Chiosis G, et al. Among authors: rosen n. Chem Biol. 2001 Mar;8(3):289-99. doi: 10.1016/s1074-5521(01)00015-1. Chem Biol. 2001. PMID: 11306353

9

Inhibition of heat shock protein 90 function by ansamycins causes the morphological and functional differentiation of breast cancer cells.

Münster PN, Srethapakdi M, Moasser MM, Rosen N. Münster PN, et al. Among authors: rosen n. Cancer Res. 2001 Apr 1;61(7):2945-52. Cancer Res. 2001. PMID: 11306472

10

The tyrosine kinase inhibitor ZD1839 ("Iressa") inhibits HER2-driven signaling and suppresses the growth of HER2-overexpressing tumor cells.

Moasser MM, Basso A, Averbuch SD, Rosen N. Moasser MM, et al. Among authors: rosen n. Cancer Res. 2001 Oct 1;61(19):7184-8. Cancer Res. 2001. PMID: 11585753

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