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1-Benzylbenzimidazoles: the discovery of a novel series of bradykinin B(1) receptor antagonists.
Guo Q, Chandrasekhar J, Ihle D, Wustrow DJ, Chenard BL, Krause JE, Hutchison A, Alderman D, Cheng C, Cortright D, Broom D, Kershaw MT, Simmermacher-Mayer J, Peng Y, Hodgetts KJ. Guo Q, et al. Among authors: broom d. Bioorg Med Chem Lett. 2008 Sep 15;18(18):5027-31. doi: 10.1016/j.bmcl.2008.08.014. Epub 2008 Aug 9. Bioorg Med Chem Lett. 2008. PMID: 18752949
TRP channels and pain.
Cortright DN, Krause JE, Broom DC. Cortright DN, et al. Biochim Biophys Acta. 2007 Aug;1772(8):978-88. doi: 10.1016/j.bbadis.2007.03.003. Epub 2007 Mar 19. Biochim Biophys Acta. 2007. PMID: 17467247 Free article. Review.
Characterization of N-(adamantan-1-ylmethyl)-5-[(3R-amino-pyrrolidin-1-yl)methyl]-2-chloro-benzamide, a P2X7 antagonist in animal models of pain and inflammation.
Broom DC, Matson DJ, Bradshaw E, Buck ME, Meade R, Coombs S, Matchett M, Ford KK, Yu W, Yuan J, Sun SH, Ochoa R, Krause JE, Wustrow DJ, Cortright DN. Broom DC, et al. J Pharmacol Exp Ther. 2008 Dec;327(3):620-33. doi: 10.1124/jpet.108.141853. Epub 2008 Sep 4. J Pharmacol Exp Ther. 2008. PMID: 18772321
215 results