Starosta AL - Search Results

1

The oxazolidinone antibiotics perturb the ribosomal peptidyl-transferase center and effect tRNA positioning.

Wilson DN, Schluenzen F, Harms JM, Starosta AL, Connell SR, Fucini P. Wilson DN, et al. Among authors: starosta al. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13339-44. doi: 10.1073/pnas.0804276105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757750 Free PMC article.

2

Identification of distinct thiopeptide-antibiotic precursor lead compounds using translation machinery assays.

Starosta AL, Qin H, Mikolajka A, Leung GY, Schwinghammer K, Nicolaou KC, Chen DY, Cooperman BS, Wilson DN. Starosta AL, et al. Chem Biol. 2009 Oct 30;16(10):1087-96. doi: 10.1016/j.chembiol.2009.09.016. Chem Biol. 2009. PMID: 19875082 Free PMC article.

3

Interplay between the ribosomal tunnel, nascent chain, and macrolides influences drug inhibition.

Starosta AL, Karpenko VV, Shishkina AV, Mikolajka A, Sumbatyan NV, Schluenzen F, Korshunova GA, Bogdanov AA, Wilson DN. Starosta AL, et al. Chem Biol. 2010 May 28;17(5):504-14. doi: 10.1016/j.chembiol.2010.04.008. Chem Biol. 2010. PMID: 20534348

4

Structural basis for translational stalling by human cytomegalovirus and fungal arginine attenuator peptide.

Bhushan S, Meyer H, Starosta AL, Becker T, Mielke T, Berninghausen O, Sattler M, Wilson DN, Beckmann R. Bhushan S, et al. Among authors: starosta al. Mol Cell. 2010 Oct 8;40(1):138-46. doi: 10.1016/j.molcel.2010.09.009. Mol Cell. 2010. PMID: 20932481 Free article.

5

Differential effects of thiopeptide and orthosomycin antibiotics on translational GTPases.

Mikolajka A, Liu H, Chen Y, Starosta AL, Márquez V, Ivanova M, Cooperman BS, Wilson DN. Mikolajka A, et al. Among authors: starosta al. Chem Biol. 2011 May 27;18(5):589-600. doi: 10.1016/j.chembiol.2011.03.010. Chem Biol. 2011. PMID: 21609840 Free PMC article.

6

Structural basis for potent inhibitory activity of the antibiotic tigecycline during protein synthesis.

Jenner L, Starosta AL, Terry DS, Mikolajka A, Filonava L, Yusupov M, Blanchard SC, Wilson DN, Yusupova G. Jenner L, et al. Among authors: starosta al. Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):3812-6. doi: 10.1073/pnas.1216691110. Epub 2013 Feb 19. Proc Natl Acad Sci U S A. 2013. PMID: 23431179 Free PMC article.

7

On the use of the antibiotic chloramphenicol to target polypeptide chain mimics to the ribosomal exit tunnel.

Mamos P, Krokidis MG, Papadas A, Karahalios P, Starosta AL, Wilson DN, Kalpaxis DL, Dinos GP. Mamos P, et al. Among authors: starosta al. Biochimie. 2013 Sep;95(9):1765-72. doi: 10.1016/j.biochi.2013.06.004. Epub 2013 Jun 14. Biochimie. 2013. PMID: 23770443

8

Ribosome rescue, nearing the end.

Starosta AL, Wilson DN. Starosta AL, et al. Cell. 2014 Feb 27;156(5):866-7. doi: 10.1016/j.cell.2014.02.028. Cell. 2014. PMID: 24581485 Free article.

9

The bacterial translation stress response.

Starosta AL, Lassak J, Jung K, Wilson DN. Starosta AL, et al. FEMS Microbiol Rev. 2014 Nov;38(6):1172-201. doi: 10.1111/1574-6976.12083. Epub 2014 Sep 26. FEMS Microbiol Rev. 2014. PMID: 25135187 Free PMC article. Review.

10

Distinct tRNA Accommodation Intermediates Observed on the Ribosome with the Antibiotics Hygromycin A and A201A.

Polikanov YS, Starosta AL, Juette MF, Altman RB, Terry DS, Lu W, Burnett BJ, Dinos G, Reynolds KA, Blanchard SC, Steitz TA, Wilson DN. Polikanov YS, et al. Among authors: starosta al. Mol Cell. 2015 Jun 4;58(5):832-44. doi: 10.1016/j.molcel.2015.04.014. Epub 2015 May 28. Mol Cell. 2015. PMID: 26028538 Free PMC article.

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