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Cancer stem cells--old concepts, new insights.
Vermeulen L, Sprick MR, Kemper K, Stassi G, Medema JP. Vermeulen L, et al. Among authors: sprick mr. Cell Death Differ. 2008 Jun;15(6):947-58. doi: 10.1038/cdd.2008.20. Epub 2008 Feb 15. Cell Death Differ. 2008. PMID: 18259194 Review.
One renegade cancer stem cell?
Borovski T, Vermeulen L, Sprick MR, Medema JP. Borovski T, et al. Among authors: sprick mr. Cell Cycle. 2009 Mar 15;8(6):803-8. doi: 10.4161/cc.8.6.7935. Epub 2009 Mar 26. Cell Cycle. 2009. PMID: 19221496
Oncogenic K-Ras turns death receptors into metastasis-promoting receptors in human and mouse colorectal cancer cells.
Hoogwater FJ, Nijkamp MW, Smakman N, Steller EJ, Emmink BL, Westendorp BF, Raats DA, Sprick MR, Schaefer U, Van Houdt WJ, De Bruijn MT, Schackmann RC, Derksen PW, Medema JP, Walczak H, Borel Rinkes IH, Kranenburg O. Hoogwater FJ, et al. Among authors: sprick mr. Gastroenterology. 2010 Jun;138(7):2357-67. doi: 10.1053/j.gastro.2010.02.046. Epub 2010 Feb 23. Gastroenterology. 2010. PMID: 20188103
Wnt activity defines colon cancer stem cells and is regulated by the microenvironment.
Vermeulen L, De Sousa E Melo F, van der Heijden M, Cameron K, de Jong JH, Borovski T, Tuynman JB, Todaro M, Merz C, Rodermond H, Sprick MR, Kemper K, Richel DJ, Stassi G, Medema JP. Vermeulen L, et al. Among authors: sprick mr. Nat Cell Biol. 2010 May;12(5):468-76. doi: 10.1038/ncb2048. Epub 2010 Apr 25. Nat Cell Biol. 2010. PMID: 20418870
Saa3 is a key mediator of the protumorigenic properties of cancer-associated fibroblasts in pancreatic tumors.
Djurec M, Graña O, Lee A, Troulé K, Espinet E, Cabras L, Navas C, Blasco MT, Martín-Díaz L, Burdiel M, Li J, Liu Z, Vallespinós M, Sanchez-Bueno F, Sprick MR, Trumpp A, Sainz B Jr, Al-Shahrour F, Rabadan R, Guerra C, Barbacid M. Djurec M, et al. Among authors: sprick mr. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):E1147-E1156. doi: 10.1073/pnas.1717802115. Epub 2018 Jan 19. Proc Natl Acad Sci U S A. 2018. PMID: 29351990 Free PMC article.
62 results