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Whole-body distribution and metabolism of [N-methyl-11C](R)-1-(2-chlorophenyl)-N-(1-methylpropyl)-3-isoquinolinecarboxamide in humans; an imaging agent for in vivo assessment of peripheral benzodiazepine receptor activity with positron emission tomography.
Roivainen A, Någren K, Hirvonen J, Oikonen V, Virsu P, Tolvanen T, Rinne JO. Roivainen A, et al. Among authors: virsu p. Eur J Nucl Med Mol Imaging. 2009 Apr;36(4):671-82. doi: 10.1007/s00259-008-1000-1. Epub 2008 Dec 3. Eur J Nucl Med Mol Imaging. 2009. PMID: 19050880
Measurement of striatal and extrastriatal dopamine transporter binding with high-resolution PET and [11C]PE2I: quantitative modeling and test-retest reproducibility.
Hirvonen J, Johansson J, Teräs M, Oikonen V, Lumme V, Virsu P, Roivainen A, Någren K, Halldin C, Farde L, Hietala J. Hirvonen J, et al. Among authors: virsu p. J Cereb Blood Flow Metab. 2008 May;28(5):1059-69. doi: 10.1038/sj.jcbfm.9600607. Epub 2008 Jan 9. J Cereb Blood Flow Metab. 2008. PMID: 18183028 Clinical Trial.
Assessment of MAO-B occupancy in the brain with PET and [11C]-L-deprenyl-D2: a dose-finding study with a novel MAO-B inhibitor, EVT 301.
Hirvonen J, Kailajärvi M, Haltia T, Koskimies S, Någren K, Virsu P, Oikonen V, Sipilä H, Ruokoniemi P, Virtanen K, Scheinin M, Rinne JO. Hirvonen J, et al. Among authors: virsu p. Clin Pharmacol Ther. 2009 May;85(5):506-12. doi: 10.1038/clpt.2008.241. Epub 2009 Jan 7. Clin Pharmacol Ther. 2009. PMID: 19129751 Clinical Trial.