Steele AD - Search Results

1

The role of calorie restriction and SIRT1 in prion-mediated neurodegeneration.

Chen D, Steele AD, Hutter G, Bruno J, Govindarajan A, Easlon E, Lin SJ, Aguzzi A, Lindquist S, Guarente L. Chen D, et al. Among authors: steele ad. Exp Gerontol. 2008 Dec;43(12):1086-93. doi: 10.1016/j.exger.2008.08.050. Epub 2008 Aug 30. Exp Gerontol. 2008. PMID: 18799131 Free PMC article.

2

Increase in activity during calorie restriction requires Sirt1.

Chen D, Steele AD, Lindquist S, Guarente L. Chen D, et al. Among authors: steele ad. Science. 2005 Dec 9;310(5754):1641. doi: 10.1126/science.1118357. Science. 2005. PMID: 16339438

3

Heat shock factor 1 regulates lifespan as distinct from disease onset in prion disease.

Steele AD, Hutter G, Jackson WS, Heppner FL, Borkowski AW, King OD, Raymond GJ, Aguzzi A, Lindquist S. Steele AD, et al. Proc Natl Acad Sci U S A. 2008 Sep 9;105(36):13626-31. doi: 10.1073/pnas.0806319105. Epub 2008 Aug 29. Proc Natl Acad Sci U S A. 2008. PMID: 18757733 Free PMC article.

4

The prion protein knockout mouse: a phenotype under challenge.

Steele AD, Lindquist S, Aguzzi A. Steele AD, et al. Prion. 2007 Apr-Jun;1(2):83-93. doi: 10.4161/pri.1.2.4346. Epub 2007 Apr 25. Prion. 2007. PMID: 19164918 Free PMC article.

5

Prion protein is expressed on long-term repopulating hematopoietic stem cells and is important for their self-renewal.

Zhang CC, Steele AD, Lindquist S, Lodish HF. Zhang CC, et al. Among authors: steele ad. Proc Natl Acad Sci U S A. 2006 Feb 14;103(7):2184-9. doi: 10.1073/pnas.0510577103. Epub 2006 Feb 7. Proc Natl Acad Sci U S A. 2006. PMID: 16467153 Free PMC article.

6

Prion protein (PrPc) positively regulates neural precursor proliferation during developmental and adult mammalian neurogenesis.

Steele AD, Emsley JG, Ozdinler PH, Lindquist S, Macklis JD. Steele AD, et al. Proc Natl Acad Sci U S A. 2006 Feb 28;103(9):3416-21. doi: 10.1073/pnas.0511290103. Epub 2006 Feb 21. Proc Natl Acad Sci U S A. 2006. PMID: 16492732 Free PMC article.

7

The power of automated high-resolution behavior analysis revealed by its application to mouse models of Huntington's and prion diseases.

Steele AD, Jackson WS, King OD, Lindquist S. Steele AD, et al. Proc Natl Acad Sci U S A. 2007 Feb 6;104(6):1983-8. doi: 10.1073/pnas.0610779104. Epub 2007 Jan 29. Proc Natl Acad Sci U S A. 2007. PMID: 17261803 Free PMC article.

8

SIRT1 transgenic mice show phenotypes resembling calorie restriction.

Bordone L, Cohen D, Robinson A, Motta MC, van Veen E, Czopik A, Steele AD, Crowe H, Marmor S, Luo J, Gu W, Guarente L. Bordone L, et al. Among authors: steele ad. Aging Cell. 2007 Dec;6(6):759-67. doi: 10.1111/j.1474-9726.2007.00335.x. Epub 2007 Sep 17. Aging Cell. 2007. PMID: 17877786 Free article.

9

Context dependent neuroprotective properties of prion protein (PrP).

Steele AD, Zhou Z, Jackson WS, Zhu C, Auluck P, Moskowitz MA, Chesselet MF, Lindquist S. Steele AD, et al. Prion. 2009 Oct-Dec;3(4):240-9. doi: 10.4161/pri.3.4.10135. Epub 2009 Oct 16. Prion. 2009. PMID: 19901559 Free PMC article.

10

Diminishing apoptosis by deletion of Bax or overexpression of Bcl-2 does not protect against infectious prion toxicity in vivo.

Steele AD, King OD, Jackson WS, Hetz CA, Borkowski AW, Thielen P, Wollmann R, Lindquist S. Steele AD, et al. J Neurosci. 2007 Nov 21;27(47):13022-7. doi: 10.1523/JNEUROSCI.3290-07.2007. J Neurosci. 2007. PMID: 18032675 Free PMC article.

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