McNally P - Search Results

1

Elafin, an elastase-specific inhibitor, is cleaved by its cognate enzyme neutrophil elastase in sputum from individuals with cystic fibrosis.

Guyot N, Butler MW, McNally P, Weldon S, Greene CM, Levine RL, O'Neill SJ, Taggart CC, McElvaney NG. Guyot N, et al. Among authors: mcnally p. J Biol Chem. 2008 Nov 21;283(47):32377-85. doi: 10.1074/jbc.M803707200. Epub 2008 Sep 17. J Biol Chem. 2008. PMID: 18799464 Free PMC article.

2

LL-37 complexation with glycosaminoglycans in cystic fibrosis lungs inhibits antimicrobial activity, which can be restored by hypertonic saline.

Bergsson G, Reeves EP, McNally P, Chotirmall SH, Greene CM, Greally P, Murphy P, O'Neill SJ, McElvaney NG. Bergsson G, et al. Among authors: mcnally p. J Immunol. 2009 Jul 1;183(1):543-51. doi: 10.4049/jimmunol.0803959. J Immunol. 2009. PMID: 19542465

3

Decreased levels of secretory leucoprotease inhibitor in the Pseudomonas-infected cystic fibrosis lung are due to neutrophil elastase degradation.

Weldon S, McNally P, McElvaney NG, Elborn JS, McAuley DF, Wartelle J, Belaaouaj A, Levine RL, Taggart CC. Weldon S, et al. Among authors: mcnally p. J Immunol. 2009 Dec 15;183(12):8148-56. doi: 10.4049/jimmunol.0901716. J Immunol. 2009. PMID: 20007580 Free PMC article.

4

High concentrations of pepsin in bronchoalveolar lavage fluid from children with cystic fibrosis are associated with high interleukin-8 concentrations.

McNally P, Ervine E, Shields MD, Dimitrov BD, El Nazir B, Taggart CC, Greene CM, McElvaney NG, Greally P. McNally P, et al. Thorax. 2011 Feb;66(2):140-3. doi: 10.1136/thx.2009.130914. Epub 2010 Dec 15. Thorax. 2011. PMID: 21160087

5

Dysregulation of TIM-3-galectin-9 pathway in the cystic fibrosis airways.

Vega-Carrascal I, Reeves EP, Niki T, Arikawa T, McNally P, O'Neill SJ, Hirashima M, McElvaney NG. Vega-Carrascal I, et al. Among authors: mcnally p. J Immunol. 2011 Mar 1;186(5):2897-909. doi: 10.4049/jimmunol.1003187. Epub 2011 Jan 24. J Immunol. 2011. PMID: 21263071

6

Vitamin D receptor agonists inhibit pro-inflammatory cytokine production from the respiratory epithelium in cystic fibrosis.

McNally P, Coughlan C, Bergsson G, Doyle M, Taggart C, Adorini L, Uskokovic MR, El-Nazir B, Murphy P, Greally P, Greene CM, McElvaney NG. McNally P, et al. J Cyst Fibros. 2011 Dec;10(6):428-34. doi: 10.1016/j.jcf.2011.06.013. Epub 2011 Jul 23. J Cyst Fibros. 2011. PMID: 21784717 Free article.

7

miR-31 dysregulation in cystic fibrosis airways contributes to increased pulmonary cathepsin S production.

Weldon S, McNally P, McAuley DF, Oglesby IK, Wohlford-Lenane CL, Bartlett JA, Scott CJ, McElvaney NG, Greene CM, McCray PB Jr, Taggart CC. Weldon S, et al. Among authors: mcnally p. Am J Respir Crit Care Med. 2014 Jul 15;190(2):165-74. doi: 10.1164/rccm.201311-1986OC. Am J Respir Crit Care Med. 2014. PMID: 24940638 Free PMC article.

8

A functional variant of elafin with improved anti-inflammatory activity for pulmonary inflammation.

Small DM, Zani ML, Quinn DJ, Dallet-Choisy S, Glasgow AM, O'Kane C, McAuley DF, McNally P, Weldon S, Moreau T, Taggart CC. Small DM, et al. Among authors: mcnally p. Mol Ther. 2015 Jan;23(1):24-31. doi: 10.1038/mt.2014.162. Epub 2014 Sep 5. Mol Ther. 2015. PMID: 25189740 Free PMC article.

9

A role for whey acidic protein four-disulfide-core 12 (WFDC12) in the regulation of the inflammatory response in the lung.

Glasgow AM, Small DM, Scott A, McLean DT, Camper N, Hamid U, Hegarty S, Parekh D, O'Kane C, Lundy FT, McNally P, Elborn JS, McAuley DF, Weldon S, Taggart CC. Glasgow AM, et al. Among authors: mcnally p. Thorax. 2015 May;70(5):426-32. doi: 10.1136/thoraxjnl-2014-206488. Epub 2015 Mar 13. Thorax. 2015. PMID: 25770093

10

miR-17 overexpression in cystic fibrosis airway epithelial cells decreases interleukin-8 production.

Oglesby IK, Vencken SF, Agrawal R, Gaughan K, Molloy K, Higgins G, McNally P, McElvaney NG, Mall MA, Greene CM. Oglesby IK, et al. Among authors: mcnally p. Eur Respir J. 2015 Nov;46(5):1350-60. doi: 10.1183/09031936.00163414. Epub 2015 Jul 9. Eur Respir J. 2015. PMID: 26160865 Free article.

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