D'Souza W - Search Results

1

Asymmetry in the lipid affinity of bihelical amphipathic peptides. A structural determinant for the specificity of ABCA1-dependent cholesterol efflux by peptides.

Sethi AA, Stonik JA, Thomas F, Demosky SJ, Amar M, Neufeld E, Brewer HB, Davidson WS, D'Souza W, Sviridov D, Remaley AT. Sethi AA, et al. J Biol Chem. 2008 Nov 21;283(47):32273-82. doi: 10.1074/jbc.M804461200. Epub 2008 Sep 19. J Biol Chem. 2008. PMID: 18805791 Free PMC article.

2

5A apolipoprotein mimetic peptide promotes cholesterol efflux and reduces atherosclerosis in mice.

Amar MJ, D'Souza W, Turner S, Demosky S, Sviridov D, Stonik J, Luchoomun J, Voogt J, Hellerstein M, Sviridov D, Remaley AT. Amar MJ, et al. J Pharmacol Exp Ther. 2010 Aug;334(2):634-41. doi: 10.1124/jpet.110.167890. Epub 2010 May 19. J Pharmacol Exp Ther. 2010. PMID: 20484557 Free PMC article.

3

Structure/function relationships of apolipoprotein a-I mimetic peptides: implications for antiatherogenic activities of high-density lipoprotein.

D'Souza W, Stonik JA, Murphy A, Demosky SJ, Sethi AA, Moore XL, Chin-Dusting J, Remaley AT, Sviridov D. D'Souza W, et al. Circ Res. 2010 Jul 23;107(2):217-27. doi: 10.1161/CIRCRESAHA.110.216507. Epub 2010 May 27. Circ Res. 2010. PMID: 20508181 Free PMC article.

4

ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis.

Fu Y, Mukhamedova N, Ip S, D'Souza W, Henley KJ, DiTommaso T, Kesani R, Ditiatkovski M, Jones L, Lane RM, Jennings G, Smyth IM, Kile BT, Sviridov D. Fu Y, et al. Cell Metab. 2013 Aug 6;18(2):225-38. doi: 10.1016/j.cmet.2013.07.003. Cell Metab. 2013. PMID: 23931754 Free article.

5

An apolipoprotein A-I mimetic peptide designed with a reductionist approach stimulates reverse cholesterol transport and reduces atherosclerosis in mice.

Ditiatkovski M, D'Souza W, Kesani R, Chin-Dusting J, de Haan JB, Remaley A, Sviridov D. Ditiatkovski M, et al. PLoS One. 2013 Jul 9;8(7):e68802. doi: 10.1371/journal.pone.0068802. Print 2013. PLoS One. 2013. PMID: 23874769 Free PMC article.

6

Global functional knockdown of ATP binding cassette transporter A1 stimulates development of atherosclerosis in apoE K/O mice.

Mukhamedova N, D'Souza W, Low H, Kesani R, Chimini G, Sviridov D. Mukhamedova N, et al. Biochem Biophys Res Commun. 2011 Sep 2;412(3):446-9. doi: 10.1016/j.bbrc.2011.07.113. Epub 2011 Aug 4. Biochem Biophys Res Commun. 2011. PMID: 21839726

7

The effect of cholesteryl ester transfer protein overexpression and inhibition on reverse cholesterol transport.

Tchoua U, D'Souza W, Mukhamedova N, Blum D, Niesor E, Mizrahi J, Maugeais C, Sviridov D. Tchoua U, et al. Cardiovasc Res. 2008 Mar 1;77(4):732-9. doi: 10.1093/cvr/cvm087. Epub 2007 Dec 4. Cardiovasc Res. 2008. PMID: 18056760

8

Enhancing apolipoprotein A-I-dependent cholesterol efflux elevates cholesterol export from macrophages in vivo.

Mukhamedova N, Escher G, D'Souza W, Tchoua U, Grant A, Krozowski Z, Bukrinsky M, Sviridov D. Mukhamedova N, et al. J Lipid Res. 2008 Nov;49(11):2312-22. doi: 10.1194/jlr.M800095-JLR200. Epub 2008 Jul 12. J Lipid Res. 2008. PMID: 18622028 Free PMC article.

9

Impact of freezing on high-density lipoprotein functionality.

Kekulawala JR, Murphy A, D'Souza W, Wai C, Chin-Dusting J, Kingwell B, Sviridov D, Mukhamedova N. Kekulawala JR, et al. Anal Biochem. 2008 Aug 15;379(2):213-5. doi: 10.1016/j.ab.2008.05.002. Epub 2008 May 7. Anal Biochem. 2008. PMID: 18503744

10

Skeletal muscle insulin resistance associated with cholesterol-induced activation of macrophages is prevented by high density lipoprotein.

Carey AL, Siebel AL, Reddy-Luthmoodoo M, Natoli AK, D'Souza W, Meikle PJ, Sviridov D, Drew BG, Kingwell BA. Carey AL, et al. PLoS One. 2013;8(2):e56601. doi: 10.1371/journal.pone.0056601. Epub 2013 Feb 21. PLoS One. 2013. PMID: 23437184 Free PMC article.

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