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Page 1
Small, non-peptide C5a receptor antagonists: part 1.
Blagg J, Mowbray C, Pryde DC, Salmon G, Schmid E, Fairman D, Beaumont K. Blagg J, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5601-4. doi: 10.1016/j.bmcl.2008.08.106. Epub 2008 Aug 31. Bioorg Med Chem Lett. 2008. PMID: 18809326
Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14.
Blagg JA, Noe MC, Wolf-Gouveia LA, Reiter LA, Laird ER, Chang SP, Danley DE, Downs JT, Elliott NC, Eskra JD, Griffiths RJ, Hardink JR, Haugeto AI, Jones CS, Liras JL, Lopresti-Morrow LL, Mitchell PG, Pandit J, Robinson RP, Subramanyam C, Vaughn-Bowser ML, Yocum SA. Blagg JA, et al. Bioorg Med Chem Lett. 2005 Apr 1;15(7):1807-10. doi: 10.1016/j.bmcl.2005.02.038. Bioorg Med Chem Lett. 2005. PMID: 15780611
Potent and selective nonpeptidic inhibitors of procollagen C-proteinase.
Fish PV, Allan GA, Bailey S, Blagg J, Butt R, Collis MG, Greiling D, James K, Kendall J, McElroy A, McCleverty D, Reed C, Webster R, Whitlock GA. Fish PV, et al. Among authors: blagg j. J Med Chem. 2007 Jul 26;50(15):3442-56. doi: 10.1021/jm061010z. Epub 2007 Jun 26. J Med Chem. 2007. PMID: 17591762
Discovery of potent & selective inhibitors of activated thrombin-activatable fibrinolysis inhibitor for the treatment of thrombosis.
Bunnage ME, Blagg J, Steele J, Owen DR, Allerton C, McElroy AB, Miller D, Ringer T, Butcher K, Beaumont K, Evans K, Gray AJ, Holland SJ, Feeder N, Moore RS, Brown DG. Bunnage ME, et al. Among authors: blagg j. J Med Chem. 2007 Nov 29;50(24):6095-103. doi: 10.1021/jm0702433. Epub 2007 Nov 9. J Med Chem. 2007. PMID: 17990866
Physiochemical drug properties associated with in vivo toxicological outcomes.
Hughes JD, Blagg J, Price DA, Bailey S, Decrescenzo GA, Devraj RV, Ellsworth E, Fobian YM, Gibbs ME, Gilles RW, Greene N, Huang E, Krieger-Burke T, Loesel J, Wager T, Whiteley L, Zhang Y. Hughes JD, et al. Among authors: blagg j. Bioorg Med Chem Lett. 2008 Sep 1;18(17):4872-5. doi: 10.1016/j.bmcl.2008.07.071. Epub 2008 Jul 24. Bioorg Med Chem Lett. 2008. PMID: 18691886
Small, non-peptide C5a receptor antagonists: part 2.
Blagg J, Mowbray C, Pryde D, Salmon G, Fairman D, Schmid E, Beaumont K. Blagg J, et al. Bioorg Med Chem Lett. 2008 Oct 15;18(20):5605-8. doi: 10.1016/j.bmcl.2008.08.101. Epub 2008 Aug 31. Bioorg Med Chem Lett. 2008. PMID: 18804369
Design and synthesis of piperazinylpyrimidinones as novel selective 5-HT(2C) agonists.
Andrews MD, Green MP, Allerton CM, Batchelor DV, Blagg J, Brown AD, Gordon DW, McMurray G, Millns DJ, Nichols CL, Watson L. Andrews MD, et al. Among authors: blagg j. Bioorg Med Chem Lett. 2009 Sep 15;19(18):5346-50. doi: 10.1016/j.bmcl.2009.07.133. Epub 2009 Aug 6. Bioorg Med Chem Lett. 2009. PMID: 19692241
106 results