The VP3 structural protein of foot-and-mouth disease virus inhibits the IFN-β signaling pathway.
Li D, Yang W, Yang F, Liu H, Zhu Z, Lian K, Lei C, Li S, Liu X, Zheng H, Shu H.
Li D, et al. Among authors: lei c.
FASEB J. 2016 May;30(5):1757-66. doi: 10.1096/fj.15-281410. Epub 2016 Jan 26.
FASEB J. 2016.
PMID: 26813975
Transient transfection and coimmunoprecipitation confirmed that the structural protein VP3 interacts with virus-induced signaling adapter (VISA), which is dependent on the C-terminal aa 111-220 of VP3. In addition, we found that FMDV VP3 inhibits the expression of VISA by …
Transient transfection and coimmunoprecipitation confirmed that the structural protein VP3 interacts with virus-induced signaling adapter (V …