Sun N - Search Results

1

5-N-methylated quindoline derivatives as telomeric g-quadruplex stabilizing ligands: effects of 5-N positive charge on quadruplex binding affinity and cell proliferation.

Lu YJ, Ou TM, Tan JH, Hou JQ, Shao WY, Peng D, Sun N, Wang XD, Wu WB, Bu XZ, Huang ZS, Ma DL, Wong KY, Gu LQ. Lu YJ, et al. Among authors: sun n. J Med Chem. 2008 Oct 23;51(20):6381-92. doi: 10.1021/jm800497p. Epub 2008 Sep 27. J Med Chem. 2008. PMID: 18821749

2

Benzothiazole-substituted benzofuroquinolinium dye: a selective switch-on fluorescent probe for G-quadruplex.

Lu YJ, Yan SC, Chan FY, Zou L, Chung WH, Wong WL, Qiu B, Sun N, Chan PH, Huang ZS, Gu LQ, Wong KY. Lu YJ, et al. Among authors: sun n. Chem Commun (Camb). 2011 May 7;47(17):4971-3. doi: 10.1039/c1cc00020a. Epub 2011 Mar 23. Chem Commun (Camb). 2011. PMID: 21431154

3

Identification of a new class of FtsZ inhibitors by structure-based design and in vitro screening.

Chan FY, Sun N, Neves MA, Lam PC, Chung WH, Wong LK, Chow HY, Ma DL, Chan PH, Leung YC, Chan TH, Abagyan R, Wong KY. Chan FY, et al. Among authors: sun n. J Chem Inf Model. 2013 Aug 26;53(8):2131-40. doi: 10.1021/ci400203f. Epub 2013 Jul 25. J Chem Inf Model. 2013. PMID: 23848971

4

Rational design of berberine-based FtsZ inhibitors with broad-spectrum antibacterial activity.

Sun N, Chan FY, Lu YJ, Neves MA, Lui HK, Wang Y, Chow KY, Chan KF, Yan SC, Leung YC, Abagyan R, Chan TH, Wong KY. Sun N, et al. PLoS One. 2014 May 13;9(5):e97514. doi: 10.1371/journal.pone.0097514. eCollection 2014. PLoS One. 2014. PMID: 24824618 Free PMC article.

5

Structure-based design, synthesis, and biological evaluation of isatin derivatives as potential glycosyltransferase inhibitors.

Wang Y, Chan FY, Sun N, Lui HK, So PK, Yan SC, Chan KF, Chiou J, Chen S, Abagyan R, Leung YC, Wong KY. Wang Y, et al. Among authors: sun n. Chem Biol Drug Des. 2014 Dec;84(6):685-96. doi: 10.1111/cbdd.12361. Epub 2014 Aug 14. Chem Biol Drug Des. 2014. PMID: 24890564

6

Antimicrobial activity of a quinuclidine-based FtsZ inhibitor and its synergistic potential with β-lactam antibiotics.

Chan FY, Sun N, Leung YC, Wong KY. Chan FY, et al. Among authors: sun n. J Antibiot (Tokyo). 2015 Apr;68(4):253-8. doi: 10.1038/ja.2014.140. Epub 2014 Oct 8. J Antibiot (Tokyo). 2015. PMID: 25293977

7

Antibacterial activity of N-methylbenzofuro[3,2-b]quinoline and N-methylbenzoindolo[3,2-b]-quinoline derivatives and study of their mode of action.

Sun N, Du RL, Zheng YY, Huang BH, Guo Q, Zhang RF, Wong KY, Lu YJ. Sun N, et al. Eur J Med Chem. 2017 Jul 28;135:1-11. doi: 10.1016/j.ejmech.2017.04.018. Epub 2017 Apr 15. Eur J Med Chem. 2017. PMID: 28426995

8

A Thiazole Orange Derivative Targeting the Bacterial Protein FtsZ Shows Potent Antibacterial Activity.

Sun N, Lu YJ, Chan FY, Du RL, Zheng YY, Zhang K, So LY, Abagyan R, Zhuo C, Leung YC, Wong KY. Sun N, et al. Front Microbiol. 2017 May 11;8:855. doi: 10.3389/fmicb.2017.00855. eCollection 2017. Front Microbiol. 2017. PMID: 28553278 Free PMC article.

9

Antibacterial activity of 3-methylbenzo[d]thiazol-methylquinolinium derivatives and study of their action mechanism.

Sun N, Du RL, Zheng YY, Guo Q, Cai SY, Liu ZH, Fang ZY, Yuan WC, Liu T, Li XM, Lu YJ, Wong KY. Sun N, et al. J Enzyme Inhib Med Chem. 2018 Dec;33(1):879-889. doi: 10.1080/14756366.2018.1465055. J Enzyme Inhib Med Chem. 2018. PMID: 29722581 Free PMC article.

10

A quinoline-based FtsZ inhibitor for the study of antimicrobial activity and synergistic effects with β-lactam antibiotics.

Fang Z, Ban L, Li Y, Yuan W, Liu Z, Liu T, Li X, Wong KY, Lu Y, Sun N, Yao X. Fang Z, et al. Among authors: sun n. J Pharmacol Sci. 2018 Jul;137(3):283-289. doi: 10.1016/j.jphs.2018.07.005. Epub 2018 Jul 17. J Pharmacol Sci. 2018. PMID: 30057277 Free article.

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