Arribas J - Search Results

1

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, Botero ML, Llonch E, Atzori F, Di Cosimo S, Maira M, Garcia-Echeverria C, Parra JL, Arribas J, Baselga J. Serra V, et al. Among authors: arribas j. Cancer Res. 2008 Oct 1;68(19):8022-30. doi: 10.1158/0008-5472.CAN-08-1385. Cancer Res. 2008. PMID: 18829560

2

Pro-tumor necrosis factor-alpha processing activity is tightly controlled by a component that does not affect notch processing.

Merlos-Suárez A, Fernández-Larrea J, Reddy P, Baselga J, Arribas J. Merlos-Suárez A, et al. Among authors: arribas j. J Biol Chem. 1998 Sep 18;273(38):24955-62. doi: 10.1074/jbc.273.38.24955. J Biol Chem. 1998. PMID: 9733803 Free article.

3

The cytoplasmic carboxy-terminal amino acid determines the subcellular localization of proTGF-(alpha) and membrane type matrix metalloprotease (MT1-MMP).

Ureña JM, Merlos-Suárez A, Baselga J, Arribas J. Ureña JM, et al. Among authors: arribas j. J Cell Sci. 1999 Mar;112 ( Pt 6):773-84. doi: 10.1242/jcs.112.6.773. J Cell Sci. 1999. PMID: 10036228

4

Cleavage of the HER2 ectodomain is a pervanadate-activable process that is inhibited by the tissue inhibitor of metalloproteases-1 in breast cancer cells.

Codony-Servat J, Albanell J, Lopez-Talavera JC, Arribas J, Baselga J. Codony-Servat J, et al. Among authors: arribas j. Cancer Res. 1999 Mar 15;59(6):1196-201. Cancer Res. 1999. PMID: 10096547

5

A role for a PDZ protein in the early secretory pathway for the targeting of proTGF-alpha to the cell surface.

Fernández-Larrea J, Merlos-Suárez A, Ureña JM, Baselga J, Arribas J. Fernández-Larrea J, et al. Among authors: arribas j. Mol Cell. 1999 Apr;3(4):423-33. doi: 10.1016/s1097-2765(00)80470-0. Mol Cell. 1999. PMID: 10230395 Free article.

6

The carboxy-terminal cysteine of the tetraspanin L6 antigen is required for its interaction with SITAC, a novel PDZ protein.

Borrell-Pagès M, Fernández-Larrea J, Borroto A, Rojo F, Baselga J, Arribas J. Borrell-Pagès M, et al. Among authors: arribas j. Mol Biol Cell. 2000 Dec;11(12):4217-25. doi: 10.1091/mbc.11.12.4217. Mol Biol Cell. 2000. PMID: 11102519 Free PMC article.

7

Trastuzumab (herceptin), a humanized anti-Her2 receptor monoclonal antibody, inhibits basal and activated Her2 ectodomain cleavage in breast cancer cells.

Molina MA, Codony-Servat J, Albanell J, Rojo F, Arribas J, Baselga J. Molina MA, et al. Among authors: arribas j. Cancer Res. 2001 Jun 15;61(12):4744-9. Cancer Res. 2001. PMID: 11406546

8

Metalloprotease-dependent protransforming growth factor-alpha ectodomain shedding in the absence of tumor necrosis factor-alpha-converting enzyme.

Merlos-Suárez A, Ruiz-Paz S, Baselga J, Arribas J. Merlos-Suárez A, et al. Among authors: arribas j. J Biol Chem. 2001 Dec 21;276(51):48510-7. doi: 10.1074/jbc.M103488200. Epub 2001 Oct 12. J Biol Chem. 2001. PMID: 11600492 Free article.

9

Mechanism of action of trastuzumab and scientific update.

Baselga J, Albanell J, Molina MA, Arribas J. Baselga J, et al. Among authors: arribas j. Semin Oncol. 2001 Oct;28(5 Suppl 16):4-11. doi: 10.1016/s0093-7754(01)90276-3. Semin Oncol. 2001. PMID: 11706390 Review.

10

ZD1839, a specific epidermal growth factor receptor (EGFR) tyrosine kinase inhibitor, induces the formation of inactive EGFR/HER2 and EGFR/HER3 heterodimers and prevents heregulin signaling in HER2-overexpressing breast cancer cells.

Anido J, Matar P, Albanell J, Guzmán M, Rojo F, Arribas J, Averbuch S, Baselga J. Anido J, et al. Among authors: arribas j. Clin Cancer Res. 2003 Apr;9(4):1274-83. Clin Cancer Res. 2003. PMID: 12684395

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