Valero V - Search Results

1

NVP-BEZ235, a dual PI3K/mTOR inhibitor, prevents PI3K signaling and inhibits the growth of cancer cells with activating PI3K mutations.

Serra V, Markman B, Scaltriti M, Eichhorn PJ, Valero V, Guzman M, Botero ML, Llonch E, Atzori F, Di Cosimo S, Maira M, Garcia-Echeverria C, Parra JL, Arribas J, Baselga J. Serra V, et al. Among authors: valero v. Cancer Res. 2008 Oct 1;68(19):8022-30. doi: 10.1158/0008-5472.CAN-08-1385. Cancer Res. 2008. PMID: 18829560

2

Phosphatidylinositol 3-kinase hyperactivation results in lapatinib resistance that is reversed by the mTOR/phosphatidylinositol 3-kinase inhibitor NVP-BEZ235.

Eichhorn PJ, Gili M, Scaltriti M, Serra V, Guzman M, Nijkamp W, Beijersbergen RL, Valero V, Seoane J, Bernards R, Baselga J. Eichhorn PJ, et al. Among authors: valero v. Cancer Res. 2008 Nov 15;68(22):9221-30. doi: 10.1158/0008-5472.CAN-08-1740. Cancer Res. 2008. PMID: 19010894 Free PMC article.

3

Downregulation of the Deiminase PADI2 Is an Early Event in Colorectal Carcinogenesis and Indicates Poor Prognosis.

Cantariño N, Musulén E, Valero V, Peinado MA, Perucho M, Moreno V, Forcales SV, Douet J, Buschbeck M. Cantariño N, et al. Among authors: valero v. Mol Cancer Res. 2016 Sep;14(9):841-8. doi: 10.1158/1541-7786.MCR-16-0034. Epub 2016 Jun 8. Mol Cancer Res. 2016. PMID: 27280713

4

A cellular model reflecting the phenotypic heterogeneity of mutant HRAS driven squamous cell carcinoma.

Cantariño N, Fernández-Figueras MT, Valero V, Musulén E, Malinverni R, Granada I, Goldie SJ, Martín-Caballero J, Douet J, Forcales SV, Buschbeck M. Cantariño N, et al. Among authors: valero v. Int J Cancer. 2016 Sep 1;139(5):1106-16. doi: 10.1002/ijc.30139. Epub 2016 May 5. Int J Cancer. 2016. PMID: 27074337

5

MacroH2A1 regulates the balance between self-renewal and differentiation commitment in embryonic and adult stem cells.

Creppe C, Janich P, Cantariño N, Noguera M, Valero V, Musulén E, Douet J, Posavec M, Martín-Caballero J, Sumoy L, Di Croce L, Benitah SA, Buschbeck M. Creppe C, et al. Among authors: valero v. Mol Cell Biol. 2012 Apr;32(8):1442-52. doi: 10.1128/MCB.06323-11. Epub 2012 Feb 13. Mol Cell Biol. 2012. PMID: 22331466 Free PMC article.

6

MacroH2A histone variants maintain nuclear organization and heterochromatin architecture.

Douet J, Corujo D, Malinverni R, Renauld J, Sansoni V, Posavec Marjanović M, Cantariño N, Valero V, Mongelard F, Bouvet P, Imhof A, Thiry M, Buschbeck M. Douet J, et al. Among authors: valero v. J Cell Sci. 2017 May 1;130(9):1570-1582. doi: 10.1242/jcs.199216. Epub 2017 Mar 10. J Cell Sci. 2017. PMID: 28283545 Free article.

7

A Cbx8-containing polycomb complex facilitates the transition to gene activation during ES cell differentiation.

Creppe C, Palau A, Malinverni R, Valero V, Buschbeck M. Creppe C, et al. Among authors: valero v. PLoS Genet. 2014 Dec 11;10(12):e1004851. doi: 10.1371/journal.pgen.1004851. eCollection 2014 Dec. PLoS Genet. 2014. PMID: 25500566 Free PMC article.

8

MacroH2A1.1 regulates mitochondrial respiration by limiting nuclear NAD⁺ consumption.

Posavec Marjanović M, Hurtado-Bagès S, Lassi M, Valero V, Malinverni R, Delage H, Navarro M, Corujo D, Guberovic I, Douet J, Gama-Perez P, Garcia-Roves PM, Ahel I, Ladurner AG, Yanes O, Bouvet P, Suelves M, Teperino R, Pospisilik JA, Buschbeck M. Posavec Marjanović M, et al. Among authors: valero v. Nat Struct Mol Biol. 2017 Nov;24(11):902-910. doi: 10.1038/nsmb.3481. Epub 2017 Oct 9. Nat Struct Mol Biol. 2017. PMID: 28991266 Free PMC article.

9

The Histone Variant MacroH2A1 Regulates Key Genes for Myogenic Cell Fusion in a Splice-Isoform Dependent Manner.

Hurtado-Bagès S, Posavec Marjanovic M, Valero V, Malinverni R, Corujo D, Bouvet P, Lavigne AC, Bystricky K, Buschbeck M. Hurtado-Bagès S, et al. Among authors: valero v. Cells. 2020 Apr 30;9(5):1109. doi: 10.3390/cells9051109. Cells. 2020. PMID: 32365743 Free PMC article.

10

Polycomb protein RING1A limits hematopoietic differentiation in myelodysplastic syndromes.

Palau A, Garz AK, Diesch J, Zwick A, Malinverni R, Valero V, Lappin K, Casquero R, Lennartsson A, Zuber J, Navarro T, Mills KI, Götze KS, Buschbeck M. Palau A, et al. Among authors: valero v. Oncotarget. 2017 Dec 1;8(70):115002-115017. doi: 10.18632/oncotarget.22839. eCollection 2017 Dec 29. Oncotarget. 2017. PMID: 29383137 Free PMC article.

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