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Studies on the structure-activity relationship of 1,3,3,4-tetra-substituted pyrrolidine embodied CCR5 receptor antagonists. Part 2: Discovery of highly potent anti-HIV agents.
Li B, Jones ED, Zhou E, Chen L, Baylis DC, Yu S, Wang M, He X, Coates JA, Rhodes DI, Pei G, Deadman JJ, Xie X, Ma D. Li B, et al. Among authors: zhou e. Bioorg Med Chem Lett. 2010 Sep 1;20(17):5334-6. doi: 10.1016/j.bmcl.2010.05.046. Epub 2010 May 19. Bioorg Med Chem Lett. 2010. PMID: 20674358
New diarylmethylpiperazines as potent and selective nonpeptidic delta opioid receptor agonists with increased In vitro metabolic stability.
Plobeck N, Delorme D, Wei ZY, Yang H, Zhou F, Schwarz P, Gawell L, Gagnon H, Pelcman B, Schmidt R, Yue SY, Walpole C, Brown W, Zhou E, Labarre M, Payza K, St-Onge S, Kamassah A, Morin PE, Projean D, Ducharme J, Roberts E. Plobeck N, et al. Among authors: zhou e, zhou f. J Med Chem. 2000 Oct 19;43(21):3878-94. doi: 10.1021/jm000228x. J Med Chem. 2000. PMID: 11052793
1,246 results