Mercè R - Search Results

1

Indene-based scaffolds. Design and synthesis of novel serotonin 5-HT6 receptor ligands.

Alcalde E, Mesquida N, Frigola J, López-Pérez S, Mercè R. Alcalde E, et al. Among authors: merce r. Org Biomol Chem. 2008 Oct 21;6(20):3795-810. doi: 10.1039/b808641a. Epub 2008 Aug 11. Org Biomol Chem. 2008. PMID: 18843410

2

Indene-based scaffolds. 2. An indole-indene switch: discovery of novel indenylsulfonamides as 5-HT6 serotonin receptor agonists.

Alcalde E, Mesquida N, López-Pérez S, Frigola J, Mercè R. Alcalde E, et al. Among authors: merce r. J Med Chem. 2009 Feb 12;52(3):675-87. doi: 10.1021/jm8009469. J Med Chem. 2009. PMID: 19159187

3

Identification of novel indanylsulfonamide guanylhydrazones as potent 5-HT6 serotonin receptor antagonists.

Mesquida N, López-Pérez S, Dinarès I, Frigola J, Mercè R, Holenz J, Pérez R, Burgueño J, Alcalde E. Mesquida N, et al. Among authors: merce r. J Med Chem. 2009 Oct 8;52(19):6153-7. doi: 10.1021/jm900796p. J Med Chem. 2009. PMID: 19739674

4

Indene-based frameworks targeting the 5-HT6 serotonin receptor: ring constraint in indenylsulfonamides using cyclic amines and structurally abbreviated counterparts.

Alcalde E, Mesquida N, López-Pérez S, Frigola J, Mercè R, Holenz J, Pujol M, Hernández E. Alcalde E, et al. Among authors: merce r. Bioorg Med Chem. 2009 Oct 15;17(20):7387-97. doi: 10.1016/j.bmc.2009.08.006. Epub 2009 Aug 8. Bioorg Med Chem. 2009. PMID: 19758807

5

7-Azetidinylquinolones as antibacterial agents. Synthesis and structure-activity relationships.

Frigola J, Parés J, Corbera J, Vañó D, Mercè R, Torrens A, Más J, Valentí E. Frigola J, et al. Among authors: merce r. J Med Chem. 1993 Apr 2;36(7):801-10. doi: 10.1021/jm00059a002. J Med Chem. 1993. PMID: 8464033

6

Medicinal chemistry driven approaches toward novel and selective serotonin 5-HT6 receptor ligands.

Holenz J, Mercè R, Díaz JL, Guitart X, Codony X, Dordal A, Romero G, Torrens A, Mas J, Andaluz B, Hernández S, Monroy X, Sánchez E, Hernández E, Pérez R, Cubí R, Sanfeliu O, Buschmann H. Holenz J, et al. Among authors: merce r. J Med Chem. 2005 Mar 24;48(6):1781-95. doi: 10.1021/jm049615n. J Med Chem. 2005. PMID: 15771424

7

Enantioseparation of basic pharmaceutical compounds by capillary electrophoresis using sulfated cyclodextrins. Application to E-6006, a novel antidepressant.

Gómez-Gomar A, Ortega E, Calvet C, Andaluz B, Mercé R, Frigola J. Gómez-Gomar A, et al. Among authors: merce r. J Chromatogr A. 2003 Mar 21;990(1-2):91-8. doi: 10.1016/s0021-9673(03)00057-8. J Chromatogr A. 2003. PMID: 12685587

8

Simultaneous separation of the enantiomers of cizolirtine and its degradation products by capillary electrophoresis.

Gómez-Gomar A, Ortega E, Calvet C, Mercé R, Frigola J. Gómez-Gomar A, et al. Among authors: merce r. J Chromatogr A. 2002 Mar 15;950(1-2):257-70. doi: 10.1016/s0021-9673(02)00017-1. J Chromatogr A. 2002. PMID: 11991000

9

Medicinal chemistry strategies to 5-HT(6) receptor ligands as potential cognitive enhancers and antiobesity agents.

Holenz J, Pauwels PJ, Díaz JL, Mercè R, Codony X, Buschmann H. Holenz J, et al. Among authors: merce r. Drug Discov Today. 2006 Apr;11(7-8):283-99. doi: 10.1016/j.drudis.2006.02.004. Drug Discov Today. 2006. PMID: 16580970 Review.

10

Discovery of 5-HT6 receptor ligands based on virtual HTS.

Tasler S, Kraus J, Wuzik A, Müller O, Aschenbrenner A, Cubero E, Pascual R, Quintana-Ruiz JR, Dordal A, Mercè R, Codony X. Tasler S, et al. Among authors: merce r. Bioorg Med Chem Lett. 2007 Nov 15;17(22):6224-9. doi: 10.1016/j.bmcl.2007.09.016. Epub 2007 Sep 8. Bioorg Med Chem Lett. 2007. PMID: 17892934

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