Malaviya R - Search Results

1

Virtual screening to successfully identify novel janus kinase 3 inhibitors: a sequential focused screening approach.

Chen X, Wilson LJ, Malaviya R, Argentieri RL, Yang SM. Chen X, et al. Among authors: malaviya r. J Med Chem. 2008 Nov 13;51(21):7015-9. doi: 10.1021/jm800662z. Epub 2008 Oct 10. J Med Chem. 2008. PMID: 18844338

2

Simplified staurosporine analogs as potent JAK3 inhibitors.

Yang SM, Malaviya R, Wilson LJ, Argentieri R, Chen X, Yang C, Wang B, Cavender D, Murray WV. Yang SM, et al. Among authors: malaviya r. Bioorg Med Chem Lett. 2007 Jan 15;17(2):326-31. doi: 10.1016/j.bmcl.2006.10.062. Epub 2006 Oct 26. Bioorg Med Chem Lett. 2007. PMID: 17088059

3

Synthetic staurosporines via a ring closing metathesis strategy as potent JAK3 inhibitors and modulators of allergic responses.

Wilson LJ, Malaviya R, Yang C, Argentieri R, Wang B, Chen X, Murray WV, Cavender D. Wilson LJ, et al. Among authors: malaviya r. Bioorg Med Chem Lett. 2009 Jun 15;19(12):3333-8. doi: 10.1016/j.bmcl.2009.04.039. Epub 2009 Apr 18. Bioorg Med Chem Lett. 2009. PMID: 19427203

4

Targeting cytosolic phospholipase A2 by arachidonyl trifluoromethyl ketone prevents chronic inflammation in mice.

Malaviya R, Ansell J, Hall L, Fahmy M, Argentieri RL, Olini GC Jr, Pereira DW, Sur R, Cavender D. Malaviya R, et al. Eur J Pharmacol. 2006 Jun 13;539(3):195-204. doi: 10.1016/j.ejphar.2006.03.018. Epub 2006 Mar 20. Eur J Pharmacol. 2006. PMID: 16712837

5

Synthesis, structure-activity relationship and in vivo antiinflammatory efficacy of substituted dipiperidines as CCR2 antagonists.

Xia M, Hou C, DeMong DE, Pollack SR, Pan M, Brackley JA, Jain N, Gerchak C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Xia M, et al. Among authors: malaviya r. J Med Chem. 2007 Nov 15;50(23):5561-3. doi: 10.1021/jm070902b. Epub 2007 Oct 11. J Med Chem. 2007. PMID: 17929797

6

Discovery of a Gut-Restricted JAK Inhibitor for the Treatment of Inflammatory Bowel Disease.

Leonard KA, Madge LA, Krawczuk PJ, Wang A, Kreutter KD, Bacani GM, Chai W, Smith RC, Tichenor MS, Harris MC, Malaviya R, Seierstad M, Johnson ME, Venable JD, Kim S, Hirst GC, Mathur AS, Rao TS, Edwards JP, Rizzolio MC, Koudriakova T. Leonard KA, et al. Among authors: malaviya r. J Med Chem. 2020 Mar 26;63(6):2915-2929. doi: 10.1021/acs.jmedchem.9b01439. Epub 2020 Mar 16. J Med Chem. 2020. PMID: 32134643

7

Potent and selective CC-chemokine receptor-2 (CCR2) antagonists as a potential treatment for asthma.

Lagu B, Gerchak C, Pan M, Hou C, Singer M, Malaviya R, Matheis M, Olini G, Cavender D, Wachter M. Lagu B, et al. Among authors: malaviya r. Bioorg Med Chem Lett. 2007 Aug 1;17(15):4382-6. doi: 10.1016/j.bmcl.2007.01.115. Epub 2007 Feb 8. Bioorg Med Chem Lett. 2007. PMID: 17587570

8

Role of Janus kinase-2 in IgE receptor-mediated leukotriene C4 production by mast cells.

Sur R, Hall J, Cavender D, Malaviya R. Sur R, et al. Among authors: malaviya r. Biochem Biophys Res Commun. 2009 Dec 18;390(3):786-90. doi: 10.1016/j.bbrc.2009.10.050. Epub 2009 Oct 14. Biochem Biophys Res Commun. 2009. PMID: 19835845

9

Different approaches to study mast cell functions.

Sur R, Cavender D, Malaviya R. Sur R, et al. Among authors: malaviya r. Int Immunopharmacol. 2007 May;7(5):555-67. doi: 10.1016/j.intimp.2007.01.009. Epub 2007 Feb 14. Int Immunopharmacol. 2007. PMID: 17386403 Review.

10

Repeated exposure of house dust mite induces progressive airway inflammation in mice: Differential roles of CCL17 and IL-13.

Malaviya R, Zhou Z, Raymond H, Wertheimer J, Jones B, Bunting R, Wilkinson P, Madireddy L, Hall L, Ryan M, Rao TS. Malaviya R, et al. Pharmacol Res Perspect. 2021 May;9(3):e00770. doi: 10.1002/prp2.770. Pharmacol Res Perspect. 2021. PMID: 33929099 Free PMC article.

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