Erythropoietin has an anti-myeloma effect - a hypothesis based on a clinical observation supported by animal studies.
Mittelman M, Zeidman A, Kanter P, Katz O, Oster H, Rund D, Neumann D.
Mittelman M, et al.
Eur J Haematol. 2004 Mar;72(3):155-65. doi: 10.1046/j.0902-4441.2003.00190.x.
Eur J Haematol. 2004.
PMID: 14962233
We proceeded and tested that hypothesis in mouse models of myeloma (Mittelman M et al., Proc Natl Acad Sci USA 98:5181,2001). In these models we confirmed that rHuEpo induced tumor regression in about 50% of the BALB/c mice inoculated with MOPC-315 myeloma cells. .. …
We proceeded and tested that hypothesis in mouse models of myeloma (Mittelman M et al., Proc Natl Acad Sci USA 98:5181,2001). …