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Synthesis and SAR studies of 3-phenoxypropyl piperidine analogues as ORL1 (NOP) receptor agonists.
Palin R, Barn DR, Clark JK, Cottney JE, Cowley PM, Crockatt M, Evans L, Feilden H, Goodwin RR, Griekspoor F, Grove SJ, Houghton AK, Jones PS, Morphy RJ, Smith AR, Sundaram H, Vrolijk D, Weston MA, Wishart G, Wren P. Palin R, et al. Among authors: jones ps. Bioorg Med Chem Lett. 2005 Feb 1;15(3):589-93. doi: 10.1016/j.bmcl.2004.11.049. Bioorg Med Chem Lett. 2005. PMID: 15664818
A series of novel, potent, and selective histone deacetylase inhibitors.
Jones P, Altamura S, Chakravarty PK, Cecchetti O, De Francesco R, Gallinari P, Ingenito R, Meinke PT, Petrocchi A, Rowley M, Scarpelli R, Serafini S, Steinkühler C. Jones P, et al. Bioorg Med Chem Lett. 2006 Dec 1;16(23):5948-52. doi: 10.1016/j.bmcl.2006.09.002. Epub 2006 Sep 20. Bioorg Med Chem Lett. 2006. PMID: 16987657
Structural and functional analysis of the human HDAC4 catalytic domain reveals a regulatory structural zinc-binding domain.
Bottomley MJ, Lo Surdo P, Di Giovine P, Cirillo A, Scarpelli R, Ferrigno F, Jones P, Neddermann P, De Francesco R, Steinkühler C, Gallinari P, Carfí A. Bottomley MJ, et al. Among authors: jones p. J Biol Chem. 2008 Sep 26;283(39):26694-704. doi: 10.1074/jbc.M803514200. Epub 2008 Jul 8. J Biol Chem. 2008. PMID: 18614528 Free PMC article.
8,813 results