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Elevated expression of Runx2 as a key parameter in the etiology of osteosarcoma.
Nathan SS, Pereira BP, Zhou YF, Gupta A, Dombrowski C, Soong R, Pho RW, Stein GS, Salto-Tellez M, Cool SM, van Wijnen AJ. Nathan SS, et al. Among authors: gupta a. Mol Biol Rep. 2009 Jan;36(1):153-8. doi: 10.1007/s11033-008-9378-1. Epub 2008 Oct 18. Mol Biol Rep. 2009. PMID: 18931939 Free PMC article.
Runx2, p53, and pRB status as diagnostic parameters for deregulation of osteoblast growth and differentiation in a new pre-chemotherapeutic osteosarcoma cell line (OS1).
Pereira BP, Zhou Y, Gupta A, Leong DT, Aung KZ, Ling L, Pho RW, Galindo M, Salto-Tellez M, Stein GS, Cool SM, van Wijnen AJ, Nathan SS. Pereira BP, et al. Among authors: gupta a. J Cell Physiol. 2009 Dec;221(3):778-88. doi: 10.1002/jcp.21921. J Cell Physiol. 2009. PMID: 19746444 Free PMC article.
MicroRNA-34c inversely couples the biological functions of the runt-related transcription factor RUNX2 and the tumor suppressor p53 in osteosarcoma.
van der Deen M, Taipaleenmäki H, Zhang Y, Teplyuk NM, Gupta A, Cinghu S, Shogren K, Maran A, Yaszemski MJ, Ling L, Cool SM, Leong DT, Dierkes C, Zustin J, Salto-Tellez M, Ito Y, Bae SC, Zielenska M, Squire JA, Lian JB, Stein JL, Zambetti GP, Jones SN, Galindo M, Hesse E, Stein GS, van Wijnen AJ. van der Deen M, et al. Among authors: gupta a. J Biol Chem. 2013 Jul 19;288(29):21307-21319. doi: 10.1074/jbc.M112.445890. Epub 2013 May 29. J Biol Chem. 2013. PMID: 23720736 Free PMC article.
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