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Cardiac myocyte-specific expression of inducible nitric oxide synthase protects against ischemia/reperfusion injury by preventing mitochondrial permeability transition.
West MB, Rokosh G, Obal D, Velayutham M, Xuan YT, Hill BG, Keith RJ, Schrader J, Guo Y, Conklin DJ, Prabhu SD, Zweier JL, Bolli R, Bhatnagar A. West MB, et al. Among authors: obal d. Circulation. 2008 Nov 4;118(19):1970-8. doi: 10.1161/CIRCULATIONAHA.108.791533. Epub 2008 Oct 20. Circulation. 2008. PMID: 18936326 Free PMC article.
Cardiomyocyte-restricted overexpression of extracellular superoxide dismutase increases nitric oxide bioavailability and reduces infarct size after ischemia/reperfusion.
Obal D, Dai S, Keith R, Dimova N, Kingery J, Zheng YT, Zweier J, Velayutham M, Prabhu SD, Li Q, Conklin D, Yang D, Bhatnagar A, Bolli R, Rokosh G. Obal D, et al. Basic Res Cardiol. 2012 Nov;107(6):305. doi: 10.1007/s00395-012-0305-1. Epub 2012 Oct 26. Basic Res Cardiol. 2012. PMID: 23099819 Free PMC article.
Genetic Deficiency of Glutathione S-Transferase P Increases Myocardial Sensitivity to Ischemia-Reperfusion Injury.
Conklin DJ, Guo Y, Jagatheesan G, Kilfoil PJ, Haberzettl P, Hill BG, Baba SP, Guo L, Wetzelberger K, Obal D, Rokosh DG, Prough RA, Prabhu SD, Velayutham M, Zweier JL, Hoetker JD, Riggs DW, Srivastava S, Bolli R, Bhatnagar A. Conklin DJ, et al. Among authors: obal d. Circ Res. 2015 Aug 14;117(5):437-49. doi: 10.1161/CIRCRESAHA.114.305518. Epub 2015 Jul 13. Circ Res. 2015. PMID: 26169370 Free PMC article.
Exercise-Induced Changes in Glucose Metabolism Promote Physiological Cardiac Growth.
Gibb AA, Epstein PN, Uchida S, Zheng Y, McNally LA, Obal D, Katragadda K, Trainor P, Conklin DJ, Brittian KR, Tseng MT, Wang J, Jones SP, Bhatnagar A, Hill BG. Gibb AA, et al. Among authors: obal d. Circulation. 2017 Nov 28;136(22):2144-2157. doi: 10.1161/CIRCULATIONAHA.117.028274. Epub 2017 Aug 31. Circulation. 2017. PMID: 28860122 Free PMC article.
TRPA1 channel contributes to myocardial ischemia-reperfusion injury.
Conklin DJ, Guo Y, Nystoriak MA, Jagatheesan G, Obal D, Kilfoil PJ, Hoetker JD, Guo L, Bolli R, Bhatnagar A. Conklin DJ, et al. Among authors: obal d. Am J Physiol Heart Circ Physiol. 2019 Apr 1;316(4):H889-H899. doi: 10.1152/ajpheart.00106.2018. Epub 2019 Feb 8. Am J Physiol Heart Circ Physiol. 2019. PMID: 30735434 Free PMC article.
Cardiospecific Overexpression of ATPGD1 (Carnosine Synthase) Increases Histidine Dipeptide Levels and Prevents Myocardial Ischemia Reperfusion Injury.
Zhao J, Conklin DJ, Guo Y, Zhang X, Obal D, Guo L, Jagatheesan G, Katragadda K, He L, Yin X, Prodhan MAI, Shah J, Hoetker D, Kumar A, Kumar V, Wempe MF, Bhatnagar A, Baba SP. Zhao J, et al. Among authors: obal d. J Am Heart Assoc. 2020 Jun 16;9(12):e015222. doi: 10.1161/JAHA.119.015222. Epub 2020 Jun 9. J Am Heart Assoc. 2020. PMID: 32515247 Free PMC article.
Integrated Multilayer Omics Reveals the Genomic, Proteomic, and Metabolic Influences of Histidyl Dipeptides on the Heart.
Yan K, Mei Z, Zhao J, Prodhan MAI, Obal D, Katragadda K, Doelling B, Hoetker D, Posa DK, He L, Yin X, Shah J, Pan J, Rai S, Lorkiewicz PK, Zhang X, Liu S, Bhatnagar A, Baba SP. Yan K, et al. Among authors: obal d. J Am Heart Assoc. 2022 Jul 5;11(13):e023868. doi: 10.1161/JAHA.121.023868. Epub 2022 Jun 22. J Am Heart Assoc. 2022. PMID: 35730646 Free PMC article.
46 results